Potential Anti-Inflammatory Effects of Eriocitrin: A Review
Abstract
Background: Inflammation is a natural reaction that the body has when exposed to physical damage. Inflammation in numerous organs implies atherosclerosis, diabetes, dermatitis, arthritis, obesity, and cancer. The review's objective was to summarize the currently known eriocitrin's anti-inflammatory effects. Methods: A review was conducted on a study of the anti-inflammatory effects of eriocitrin conducted from January 2010 to April 2021. Results: Based on eligibility criteria, six studies were included in this study consisting of in vitro and in vivo studies. Some pharmacological studies have suggested that eriocitrin has the potential to treat diseases involving inflammatory responses. Nitric Oxide (NO), IL-1β, IL-6, IL-8, TNF-α, NF-κB, MPO, MAPK, and MMP-9 secretion were reduced by eriocitrin, inhibiting cell apoptosis, and the production of pro-inflammatory cytokines, but increases the content of IL-10, Nrf2, DUSP14, HO-1, and NQ01. Conclusions: Eriocitrin has been shown to have anti-inflammatory effects in both in vitro and in vivo studies.
Keywords: eriocitrin; flavonoids; inflammation
Keywords:
eriocitrin, flavonoids, inflammationDOI
https://doi.org/10.22270/jddt.v12i3.5456References
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