Liquid Chromatography-Mass Spectrometry based Phytochemical Profiling of Marine Macroalga Ulva compressa Methanol Extract
Abstract
Marine macroalgae are widely recognized as vital sources of bioactive compounds, having prospective applications in pharmaceuticals, nutraceuticals, and biotechnology. As global demands for natural therapeutics continue to grow, marine macroalgae, especially Ulva species, have emerged as a promising candidate due to their diverse profiles of phytochemicals. In such cases, qualitative phytochemical analysis is fundamental in determining these bioactive constituents, as well as their potential functional activities. In this study, the methanolic extract of Ulva compressa was subjected to Liquid Chromatography-Mass Spectrometry analysis in both positive (ESI+) and negative (ESI-) Electrospray Ionization modes to characterize its phytochemical composition in detail. Using ESI-, a total of 66 phytochemicals were detected, and 29 by ESI+, showing the phytochemical richness of the marine alga. The detected phytochemicals belonged to many biologically vital chemical classes, which include flavonoids, phenolics, peptides, fatty acids, lipids, terpenoids, and glycosides. These findings support the application of Ulva compressa as a marine-based resource for drug discovery and functional product development. This work also highlights the potential of LC-MS as an effective technique for marine phytochemical profiling, providing in-depth molecular insights.
Keywords: LC-MS, Phytochemical Profiling, Ulva compressa
Keywords:
LC-MS, Ulva compressa, Phytochemical analysisDOI
https://doi.org/10.22270/jddt.v15i7.7216References
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