Profile of Bioactive Phyto-compounds in Essential Oil of Cymbopogon martinii from Palani Hills, Western Ghats, INDIA

Authors

  • C. Soorya Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India
  • S. Balamurugan Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India
  • Afroze Naveed Basha PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani - 624601, Dindigul District, TamilNadu, India
  • C. Kandeepan PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani - 624601, Dindigul District, TamilNadu, India
  • S. Ramya Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India
  • R. Jayakumararaj Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

Abstract

Worldwide interest in use of plants based natural products (PBNPs) has been growing, and its beneficial effects being rediscovered for the development of novel drugs. Literature survey on indigenous traditional knowledge bestows ethnopharmacological potentials of PBNPs that has inspired current research in drug design and discovery; PBNPs provide baseline for the development of novel drug leads against various pharmacological targets. Studies indicate that Cymbopogon martini Essential Oil (CMEO) exhibit wide range of biological activities such as hepatoprotective, antifungal, insecticide, antioxidant and antibacterial. Pharmacological properties in Palmarosa Essential Oil (PEO) may be due to the presence of compounds like 4-Decen-6-yne, (Z), 2-Ethylimino-4-methyl-pent-3-enenitrile, Dihydrocarvyl acetate, 2-Methylbenzaldehyde, Geranyl butyrate, 1,5,9,9-Tetramethyl-1,4,7-cycloundecatriene. However, its application is limited because of the odor, color and taste. In the present study, GCMS based profile of bioactive phyto-compounds in essential oil of Cymbopogon martinii along with its physiochemical, biological, molecular, pharmacological and drugable properties has been envisaged.

Keywords: Cymbopogon martinii Essential Oil (CMEO); Pharmacological Activity; ADMET Properties; Bioactive Compounds; Plant Based Natural Products (PBNPs);

Keywords:

Cymbopogon martinii Essential Oil (CMEO), Pharmacological Activity, ADMET Properties, Bioactive Compounds, Plant Based Natural Products (PBNPs)

DOI

https://doi.org/10.22270/jddt.v11i4.4887

Author Biographies

C. Soorya, Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

S. Balamurugan, Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

Afroze Naveed Basha, PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani - 624601, Dindigul District, TamilNadu, India

PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani - 624601, Dindigul District, TamilNadu, India

C. Kandeepan, PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani - 624601, Dindigul District, TamilNadu, India

PG and Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani - 624601, Dindigul District, TamilNadu, India

S. Ramya, Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

R. Jayakumararaj, Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

Department of Botany, Government Arts College, Melur– 625106, Madurai District, Tamil Nadu, India

References

Jummes B, Sganzerla WG, da Rosa CG, Noronha CM, Nunes MR, Bertoldi FC, Barreto PL. Antioxidant and antimicrobial poly-ε-caprolactone nanoparticles loaded with Cymbopogon martinii essential oil. Biocatalysis and Agricultural Biotechnology. 2020; 23:101499. https://doi.org/10.1016/j.bcab.2020.101499

Avoseh O, Oyedeji O, Rungqu P, Nkeh-Chungag B, Oyedeji A. Cymbopogon species; ethnopharmacology, phytochemistry and the pharmacological importance. Molecules. 2015; 20(5):7438-53. https://doi.org/10.3390/molecules20057438

Prashar A, Hili P, Veness RG, Evans CS. Antimicrobial action of palmarosa oil (Cymbopogon martinii) on Saccharomyces cerevisiae. Phytochemistry. 2003; 63(5):569-75. https://doi.org/10.1016/S0031-9422(03)00226-7

Raina VK, Srivastava SK, Aggarwal KK, Syamasundar KV, Khanuja SP. Essential oil composition of Cymbopogon martinii from different places in India. Flavour and Fragrance Journal. 2003; 18(4):312-5. https://doi.org/10.1002/ffj.1222

Kumar R, Srivastava M, Dubey NK. Evaluation of Cymbopogon martinii oil extract for control of postharvest insect deterioration in cereals and legumes. Journal of food protection. 2007; 70(1):172-8. https://doi.org/10.4315/0362-028X-70.1.172

Kalagatur NK, Nirmal Ghosh OS, Sundararaj N, Mudili V. Antifungal activity of chitosan nanoparticles encapsulated with Cymbopogon martinii essential oil on plant pathogenic fungi Fusarium graminearum. Frontiers in pharmacology. 2018; 9:610. https://doi.org/10.3389/fphar.2018.00610

Mishra PK, Kedia A, Dubey NK. Chemically characterized Cymbopogon martinii (Roxb.) Wats. essential oil for shelf life enhancer of herbal raw materials based on antifungal, antiaflatoxigenic, antioxidant activity and favorable safety profile. Plant Biosyst. 2015; 150:1313-1322. https://doi.org/10.1080/11263504.2015.1054450

Caballero-Gallardo K, Olivero-Verbel J, Stashenko EE. Repellency and toxicity of essential oils from Cymbopogon martinii, Cymbopogon flexuosus and Lippia origanoides cultivated in Colombia against Tribolium castaneum. Journal of Stored Products Research. 2012; 50:62-5. https://doi.org/10.1016/j.jspr.2012.05.002

Andrade BF, Conti BJ, Santiago KB, Fernandes A, Sforcin JM. C ymbopogon martinii essential oil and geraniol at non-cytotoxic concentrations exerted immunomodulatory/anti-inflammatory effects in human monocytes. Journal of Pharmacy and Pharmacology. 2014; 66(10):1491-6. https://doi.org/10.1111/jphp.12278

Al-Shalah LA, Hindi NK, Mohsen IH. Essential Oils. Essential Oils: Bioactive Compounds, New Perspectives and Applications. 2020; 9:29.

Chávez-González ML, Rodríguez-Herrera R, Aguilar CN. Essential oils: A natural alternative to combat antibiotics resistance. Antibiotic Resistance-Mechanisms and New Antimicrobial Approaches; Kon, K., Rai, M., Eds. 2016; 227-37. https://doi.org/10.1016/B978-0-12-803642-6.00011-3

Atanasov AG, Waltenberger B, Pferschy-Wenzig EM, Linder T, Wawrosch C, Uhrin P, Temml V, Wang L, Schwaiger S, Heiss EH, Rollinger JM. Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnology advances. 2015; 33(8):1582-614. https://doi.org/10.1016/j.biotechadv.2015.08.001

Rašković A, Milanović I, Pavlović N, Ćebović T, Vukmirović S, Mikov M. Antioxidant activity of rosemary (Rosmarinus officinalis L.) essential oil and its hepatoprotective potential. BMC complementary and alternative medicine. 2014; 14(1):1-9. https://doi.org/10.1186/1472-6882-14-225

Khan MS, Ahmad I. In vitro antifungal, anti-elastase and anti-keratinase activity of essential oils of Cinnamomum-, Syzygium- and Cymbopogon-species against Aspergillus fumigates and Trichophyto rubrum. Phytomedicine. 2011; 19:48-55 https://doi.org/10.1016/j.phymed.2011.07.005

Yoon MY, Cha B, Kim JC Recent trends in studies on botanical fungicides in agriculture. The plant pathology journal. 2013; 29(1):1. https://doi.org/10.5423/PPJ.RW.05.2012.0072

Matthew KM. Flora of the Tamilnadu Carnatic. The Rapinat Herbarium, St. Joseph's College, Tiruchirapalli, India; 1981

Gamble JS, Fischer CE. Flora of the Presidency of Madras. London, UK: West, Newman and Adlard; 1915. https://doi.org/10.5962/bhl.title.21628

Eleyinmi AF Chemical composition and antibacterial of Gongronema latifolium J Zhejiang Univ Sci B 2007; 8:352-358 https://doi.org/10.1631/jzus.2007.B0352

Zhou Y, Wu F, Li L, Shen X, Chen G, Wang X, Liang X, Tan M, Huang Z. Computational approaches in preclinical studies on drug discovery and development. Frontiers in Chemistry. 2020; 8:726-31. https://doi.org/10.3389/fchem.2020.00726

Ramya S, Neethirajan K, Jayakumararaj R. Profile of bioactive compounds in Syzygium cumini-a review. Journal of Pharmacy research. 2012; 5(8):4548-53.

Gaba J, Bhardwaj G, Sharma A. Lemongrass. In Antioxidants in Vegetables and Nuts-Properties and Health Benefits 2020 (pp. 75-103). Springer, Singapore. https://doi.org/10.1007/978-981-15-7470-2_4

Published

2021-07-15
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How to Cite

1.
Soorya C, Balamurugan S, Basha AN, Kandeepan C, Ramya S, Jayakumararaj R. Profile of Bioactive Phyto-compounds in Essential Oil of Cymbopogon martinii from Palani Hills, Western Ghats, INDIA. J. Drug Delivery Ther. [Internet]. 2021 Jul. 15 [cited 2026 Jan. 13];11(4):60-5. Available from: https://www.jddtonline.info/index.php/jddt/article/view/4887

How to Cite

1.
Soorya C, Balamurugan S, Basha AN, Kandeepan C, Ramya S, Jayakumararaj R. Profile of Bioactive Phyto-compounds in Essential Oil of Cymbopogon martinii from Palani Hills, Western Ghats, INDIA. J. Drug Delivery Ther. [Internet]. 2021 Jul. 15 [cited 2026 Jan. 13];11(4):60-5. Available from: https://www.jddtonline.info/index.php/jddt/article/view/4887

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