Profile of Phytochemicals and GCMS Analysis of Bioactive Compounds in Natural Dried-Seed Removed Ripened Pods Methanolic Extracts of Moringa oleifera

Authors

  • K. Suganandam Department of Chemistry, Velammal College of Engineering & Technology, Viraganoor, Madurai-625009, TN, India
  • A. Jeevalatha Department of Zoology, GTN Arts College, Dindigul - 624005, TN, India
  • C. Kandeepan PG & Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani – 624601, TN, India
  • N. Kavitha PG & Research Department of Chemistry, Arulmigu Palaniandavar College of Arts & Culture, Palani – 624601, TN, India
  • N. Senthilkumar Institute of Forest Genetics & Tree Breeding (IFGTB), Indian Council of Forestry Research & Education (ICFRE), Coimbatore – 641002, TN, India
  • S. Sutha Department of Medicinal Botany, Govt. Siddha Medical College, Palayamkottai, Tamil Nadu, India
  • Mohamed Ali Seyed Department of Biochemistry, Faculty of Science, University of Tabuk, Tabuk, 47731, Kingdom of Saudi Arabia
  • Sanyam Gandhi Regulatory Affairs, Takeda Pharmaceuticals, Boston, MA, 02139, USA
  • S. Ramya PG Department of Zoology, Yadava College (Men), Thiruppalai - 625014, Madurai, TN, India
  • G Grace Lydial Pushpalatha PG Department of Botany, Sri Meenakshi Government Arts College, Madurai – 625002, TN, India
  • GC. Abraham PG & Research Department of Botany, The American College, Madurai – 625002, TamilNadu, India
  • R. Jayakumararaj Department of Botany, Government Arts College, Melur – 625106, Madurai District, TN, India

Abstract

Moringa oleifera has been reported to be the store-house of wide range of bioactive compounds. Most commonly used plant part has been the leaves which are reported to be rich in Vitamins, Carotenoids, Polyphenols, Phenolic Acids, Flavonoids Alkaloids, Glucosinolates, Isocyanides, Tannins and Saponins. Moringa leaves are used as Keerai while, green pods are commonly used as vegetable in the traditional preparation of Sambar in South-India. MO is gaining popularity because of its nutrient-rich root, leaves, flowers and fruits, having immense traditional medicinal uses and proved pharmacological properties. Not much of work has been carried out on analysis of bioactive compounds present in the pods. In the present study an attempt has been made to screen and analyze the range of bioactive compounds present in Moringa oleifera seed removed ripened natural dried pods. Phytochemical screening and GCMS analysis revealed the presence of 12 compounds namely - 7-Octadecyne, 2-methyl- (C19H36); 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (C20H40O); 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (C20H40O); 6,9,12,15-Docosatetraenoic acid, me (C23H38O2); Cyclohexanol, 5-methyl-2-(1-methylethyl)- (C10H20O); 3,7,11,15-Tetramethyl-2-hexadecen-1-ol (C20H40O); Palmitic acid vinyl ester (C18H34O2); .gamma.-Tocopherol (C28H48O2); Vitamin E (C29H50O2); Cholesta-7,9(11)-dien-3-ol, 4,4-dim (C29H48O); gamma.-Sitosterol (C29H50O); Stigmasta-5,24(28)-dien-3-ol, (3.beta.,24Z)- (C29H48O). Further, in-silico ADMET analysis is expected to provide in-death physiochemical and biomolecular details of these molecules in order to exploit them for production of novel drugs for the pharma market with wide array of bio medical applications.

Keywords: Bioactive Compounds; GCMS; Phytochemical Screening; MOPME; Plant Based Natural Products;

Keywords:

Bioactive Compounds, GCMS, Phytochemical Screening, MOPME, Plant Based Natural Products

DOI

https://doi.org/10.22270/jddt.v12i5-S.5657

Author Biographies

K. Suganandam, Department of Chemistry, Velammal College of Engineering & Technology, Viraganoor, Madurai-625009, TN, India

Department of Chemistry, Velammal College of Engineering & Technology, Viraganoor, Madurai-625009, TN, India

A. Jeevalatha, Department of Zoology, GTN Arts College, Dindigul - 624005, TN, India

Department of Zoology, GTN Arts College, Dindigul - 624005, TN, India

C. Kandeepan, PG & Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani – 624601, TN, India

PG & Research Department of Zoology, Arulmigu Palaniandavar College of Arts & Culture, Palani – 624601, TN, India

N. Kavitha, PG & Research Department of Chemistry, Arulmigu Palaniandavar College of Arts & Culture, Palani – 624601, TN, India

PG & Research Department of Chemistry, Arulmigu Palaniandavar College of Arts & Culture, Palani – 624601, TN, India

N. Senthilkumar, Institute of Forest Genetics & Tree Breeding (IFGTB), Indian Council of Forestry Research & Education (ICFRE), Coimbatore – 641002, TN, India

Institute of Forest Genetics & Tree Breeding (IFGTB), Indian Council of Forestry Research & Education (ICFRE), Coimbatore – 641002, TN, India

S. Sutha, Department of Medicinal Botany, Govt. Siddha Medical College, Palayamkottai, Tamil Nadu, India

Department of Medicinal Botany, Govt. Siddha Medical College, Palayamkottai, Tamil Nadu, India

Mohamed Ali Seyed, Department of Biochemistry, Faculty of Science, University of Tabuk, Tabuk, 47731, Kingdom of Saudi Arabia

Department of Biochemistry, Faculty of Science, University of Tabuk, Tabuk, 47731, Kingdom of Saudi Arabia

Sanyam Gandhi, Regulatory Affairs, Takeda Pharmaceuticals, Boston, MA, 02139, USA

Regulatory Affairs, Takeda Pharmaceuticals, Boston, MA, 02139, USA

S. Ramya, PG Department of Zoology, Yadava College (Men), Thiruppalai - 625014, Madurai, TN, India

PG Department of Zoology, Yadava College (Men), Thiruppalai - 625014, Madurai, TN, India

G Grace Lydial Pushpalatha, PG Department of Botany, Sri Meenakshi Government Arts College, Madurai – 625002, TN, India

PG Department of Botany, Sri Meenakshi Government Arts College, Madurai – 625002, TN, India

GC. Abraham, PG & Research Department of Botany, The American College, Madurai – 625002, TamilNadu, India

PG & Research Department of Botany, The American College, Madurai – 625002, TamilNadu, India

R. Jayakumararaj, Department of Botany, Government Arts College, Melur – 625106, Madurai District, TN, India

Department of Botany, Government Arts College, Melur – 625106, Madurai District, TN, India

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2022-10-15
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How to Cite

1.
Suganandam K, Jeevalatha A, Kandeepan C, Kavitha N, Senthilkumar N, Sutha S, et al. Profile of Phytochemicals and GCMS Analysis of Bioactive Compounds in Natural Dried-Seed Removed Ripened Pods Methanolic Extracts of Moringa oleifera. J. Drug Delivery Ther. [Internet]. 2022 Oct. 15 [cited 2026 Jan. 15];12(5-S):133-41. Available from: https://www.jddtonline.info/index.php/jddt/article/view/5657

How to Cite

1.
Suganandam K, Jeevalatha A, Kandeepan C, Kavitha N, Senthilkumar N, Sutha S, et al. Profile of Phytochemicals and GCMS Analysis of Bioactive Compounds in Natural Dried-Seed Removed Ripened Pods Methanolic Extracts of Moringa oleifera. J. Drug Delivery Ther. [Internet]. 2022 Oct. 15 [cited 2026 Jan. 15];12(5-S):133-41. Available from: https://www.jddtonline.info/index.php/jddt/article/view/5657

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