A Review on Deprescribing in Elderly
Abstract
Deprescribing can be defined as the process of stopping a medication or reducing its dose to reduce adverse effects and improve health outcomes. Elderly people with co morbidities usually have a risk of adverse drug events and these events can only be treated by medicines. Despite the benefits offered by these medicines, older patients are at a high risk of harm caused by these medications. The use of multiple medications for treating the comorbidities may also leads to severe health problems. Deprescribing help to reduce the risk related to inappropriate medicines. Deprescribing is usually a patient centered process which helps to withdraw drugs which are harmful to be prescribed to older patients. Several explicit and implicit tools have been developed internationally to identify these inappropriate medications. Deprescribing of inappropriate medicines would help to reduces drug-related harm and improves the quality of life of older adults.
Keywords: Deprescribing, polypharmacy, older adults
Keywords:
Deprescribing, polypharmacy, older adultsDOI
https://doi.org/10.22270/jddt.v11i4.4871References
Le Bosquet K, Barnett, N Minshull J, Deprescribing: Practical ways to support person-centered, evidence-based deprescribing, Pharmacy, 2019; 7(3):129-139 https://doi.org/10.3390/pharmacy7030129
Woodford HJ, Fisher J, New horizons in deprescribing for older people, Age and ageing, 2019; 48(6):768-775. https://doi.org/10.1093/ageing/afz109
Potter K, Flicker L, Page A, Etherton-Beer C, Deprescribing in frail older people: a randomized contolled trail, PloS one, 2016; 11(3):149-155 https://doi.org/10.1371/journal.pone.0149984
HilmerSN, GnjidicD, The effects of polypharmacy in older adults, Clinical Pharmacology & Therapeutics, 2009; 85(1):86-8 https://doi.org/10.1038/clpt.2008.224
Le Couteur D, Banks E, Gnjidic D, McLzchlan A, Deprescribing, Australian prescriber, 2011; 34(6):182-185 https://doi.org/10.18773/austprescr.2011.095
Liacos M, Page AT, Etherton-Beer C, Deprescribing in older people,Australian prescriber, 2020; 43(4):114-120 https://doi.org/10.18773/austprescr.2020.033
Curtin D, Gallagher P,O' Mahony D, Deprescribing in older people approaching end-of-life: development and validation of STOPP Frail version 2,Age and ageing, 2021; 50(2):465-471. https://doi.org/10.1093/ageing/afaa159
Planton J, Edlund B, Strategies of reducing polypharmacy in older adults, Journal of gerontological nursing, 2019; 36(1):8-12. https://doi.org/10.3928/00989134-20091204-03
Reeve E, To J, Hendrix I, Shakib S, Roberts MS, Wiese MD, Patient barriers to and enablers of deprescribing: a systematic review, Drugs & ageing, 2013;30(10):793-807. https://doi.org/10.1007/s40266-013-0106-8
Salahudeen MS, Deprescribing medications in older people: a narrative review, Drugs of Today, 2018; 54(8):3489-3498. https://doi.org/10.1358/dot.2018.54.8.2856495
Published
Abstract Display: 464
PDF Downloads: 623
PDF Downloads: 42 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).

.