The effect of Coffee on some cardiovascular parameters in hypertensive and normotensive patients at Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, (COOUTH), Awka, Nigeria

Authors

  • CCA Azikiwe Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria
  • Chukwuma Chijioke Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria
  • BU Ogbonna Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria
  • Chibundo Uchenna Nwaneli Department of Internal Medicine, Nnamdi Azikiwe University, Nnewi, Nigeria https://orcid.org/0000-0001-6084-8781
  • FC Chukwuka GOPD, Federal University Teaching Hospital, Owerri, Nigeria
  • JO Egbunike GOPD, University of Abuja Teaching Hospital, FCT, Nigeria

Abstract

Background: Studies have reported some health benefits of coffee consumption however it has been documented that coffee is associated with acute elevation of blood pressure and perhaps leading to chronic hypertension and poor control. 

Aim: This study aims to determine the acute effects of coffee on some cardiovascular parameters in hypertensive and normotensive patients at a tertiary health institution in South -East region of Nigeria.

Method: 500 adul t volunteers who met the inclusion criteria consisting of 250 hypertensive patients and 250 normotensive individuals participated in the study. 2grams of coffee granules were dissolved in 200ml of hot water and served to study participants. Basal values of blood pressure, Pulse rate and finger oxygen saturation (SPo2) were obtained before consumption. These parameters were then measured at 15mins post consumption and at every 30mins intervals for 5hours. Data was analysed using SPSS version 29. Mean, Standard deviation (SD), Standard error of the mean (SEM) and P-values were calculated.

Results: The hypertensive group consisted of 135 females and 115 males with a mean age of 57.72±11.55 while the normotensives consisted of 112 femal es and 138 males with a mean age of 50.10±11.90. From 30mins to the first 2 hours post consumption there was a significant elevation of systolic blood pressure (P≤0.001) as well as the diastolic pressure (P≤0.001) in both hypertensive and normotensive group. At 4 hours post consumption, the blood pressures of both study groups have returned to the baseline values. The pulse rate of both groups started rising about 15 minutes post coffee intake. The pulse rate of both groups started dropping 2 hours post coffee administration. At 3 hours, pulse rates of both study groups had returned to their basal levels. The oxygen saturation (SpO2) in both groups did not vary from baseline till end of the study.

Conclusion: Coffee caused transient elevation of blood pressure and increased heart rate from baseline in both hypertensive patients and normotensives. This observation may necessitate review of recommendation physicians give to hypertensive patients to modify the rate of consumption of coffee to achieve a better control of blood pressure

 

Keywords:

Coffee, Hypertension, Blood pressure, Pulse rate, Oxygen saturation

DOI

https://doi.org/10.22270/jddt.v16i7.7881

Author Biographies

CCA Azikiwe , Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria

Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria

Chukwuma Chijioke , Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria

Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria

BU Ogbonna, Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria

Department of Pharmacology and Therapeutics, Chukwuemeka Odumegwu Ojukwu University (COOU), Awka, Nigeria

Chibundo Uchenna Nwaneli , Department of Internal Medicine, Nnamdi Azikiwe University, Nnewi, Nigeria

Department of Internal Medicine, Nnamdi Azikiwe University, Nnewi, Nigeria

FC Chukwuka , GOPD, Federal University Teaching Hospital, Owerri, Nigeria

GOPD, Federal University Teaching Hospital, Owerri, Nigeria

JO Egbunike , GOPD, University of Abuja Teaching Hospital, FCT, Nigeria

GOPD, University of Abuja Teaching Hospital, FCT, Nigeria

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Published

2026-07-15
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How to Cite

1.
Azikiwe CA, Chijioke C, Ogbonna B, Nwaneli CU, Chukwuka F, Egbunike J. The effect of Coffee on some cardiovascular parameters in hypertensive and normotensive patients at Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, (COOUTH), Awka, Nigeria. J. Drug Delivery Ther. [Internet]. 2026 Jul. 15 [cited 2026 Jul. 16];16(7):143-8. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7881

How to Cite

1.
Azikiwe CA, Chijioke C, Ogbonna B, Nwaneli CU, Chukwuka F, Egbunike J. The effect of Coffee on some cardiovascular parameters in hypertensive and normotensive patients at Chukwuemeka Odumegwu Ojukwu University Teaching Hospital, (COOUTH), Awka, Nigeria. J. Drug Delivery Ther. [Internet]. 2026 Jul. 15 [cited 2026 Jul. 16];16(7):143-8. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7881