GC-MS analysis of ethanolic extract of Momordica charantia fruit

Authors

  • Brij Raj Singh Department of Pharmacognosy, Malti Memorial Trust CSM Group of Institutions, Faculty of B.Pharmacy, 8th Mile stone Rewa Road, Iradatganj, Prayagraj 212111, U.P., India. https://orcid.org/0009-0001-3572-4450
  • Amita Verma Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, India. https://orcid.org/0000-0001-6653-7335
  • Vinay Kumar Yadav Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, India.

Abstract

Researchers are particularly interested in medicinal plants because most pharmaceutical businesses use them to make pharmaceutical compounds. Traditionally, especially in India, a large number of compounds utilized as food colors, tastes, perfumes, and medicinal biochemicals are obtained from plants. Most herbal treatments and their derivative products were often made from crude plant extracts, which are a complex mixture of various phytochemical constituents (plant secondary metabolites). The chemical properties of these components differ greatly between species. The GC-MS method employed for the study of the extracted materials is an interesting instrument for figuring out the concentration of specific active principles in herbs used in the food, pharmaceutical, cosmetic, or pharmaceutical industries. The aim of this work was to discover bioactive compounds from the ethanolic fruit extract of Momordica charantia using gas chromatography and mass spectrometry (GC-MS). The GCMS-QP2010 Ultra Version was used to perform GCMS analysis of the ethanolic extract in accordance with standard procedure. The findings demonstrated the presence of various 32 phytochemicals, including heptacosanoic acid, Eicosanoic acid,Eicosanoic acid, Undecanoic acid, docanoic acid, decanal, 1-(Pyrrolidin-3-yl) pyrazole, Tricotanoic acid  in the ethanolic extract of M. charantia. Because of the ethanolic extract contains secondary metabolites, the M. charantia may have anti-inflammatory, Antifungal, neurological disorders, anti-tumor, anti-microbial, antioxidant, and antidiabetic properties. These results support the traditional use of M. charantia for a number of ailments. Further research is needed to determine the extract's active ingredient and elucidate its exact method of action in a range of ailments.

Keywords: 1-(Pyrrolidin-3-yl) pyrazole, M. charantia, Heptacosanoic acid, Eicosanoic acid, Decanal

Keywords:

1-(Pyrrolidin-3-yl) pyrazole, M. charantia, Heptacosanoic acid, Eicosanoic acid, Decanal

DOI

https://doi.org/10.22270/jddt.v16i7.7858

Author Biographies

Brij Raj Singh, Department of Pharmacognosy, Malti Memorial Trust CSM Group of Institutions, Faculty of B.Pharmacy, 8th Mile stone Rewa Road, Iradatganj, Prayagraj 212111, U.P., India.

Department of Pharmacognosy, Malti Memorial Trust CSM Group of Institutions, Faculty of B.Pharmacy, 8th Mile stone Rewa Road, Iradatganj, Prayagraj 212111, U.P., India.

Amita Verma, Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, India.

Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, India.

Vinay Kumar Yadav, Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, India.

Bioorganic and Medicinal Chemistry Research Laboratory, Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, India.

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Published

2026-07-15
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How to Cite

1.
Singh BR. GC-MS analysis of ethanolic extract of Momordica charantia fruit. J. Drug Delivery Ther. [Internet]. 2026 Jul. 15 [cited 2026 Jul. 16];16(7):33-4. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7858

How to Cite

1.
Singh BR. GC-MS analysis of ethanolic extract of Momordica charantia fruit. J. Drug Delivery Ther. [Internet]. 2026 Jul. 15 [cited 2026 Jul. 16];16(7):33-4. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7858