Development and Validation of Stability Indicating RP-HPLC Method for the Estimation of Lasmiditan in tablet dosage form

Authors

  • Rahul Ramhari Darade Department of Quality Assurance, JSPM University School of Pharmaceutical Science, Wagholi, Pune, Maharashtra, India-412207.
  • Sagar B Wankhede Assistant Professor, Department of Quality Assurance Techniques, Dean of JSPM University School of Pharmaceutical Science, Wagholi, Pune, Maharashtra, India-412207.

Abstract

HPLC, in particular, offers high resolution, accuracy, and reproducibility, making it indispensable for routine quality control and advanced research applications. Method development in HPLC involves systematic selection and optimization of mobile phase composition, column chemistry, detection wavelength, and operational parameters to achieve reliable separation and quantification. Analytical method validation, guided by ICH and USP standards, ensures that developed methods meet essential criteria, including accuracy, precision, linearity, specificity, robustness, and sensitivity.

Keywords: Lasmiditan, Development, RP-HPLC, Accuracy, linearity, Limit of detection (LOD) and Limit of quantification (LOQ).

Keywords:

Lasmiditan, Development, RP-HPLC, Accuracy, , linearity, , Limit of detection (LOD) , Limit of quantification (LOQ).

DOI

https://doi.org/10.22270/jddt.v16i1.7516

Author Biographies

Rahul Ramhari Darade, Department of Quality Assurance, JSPM University School of Pharmaceutical Science, Wagholi, Pune, Maharashtra, India-412207.

Department of Quality Assurance, JSPM University School of Pharmaceutical Science, Wagholi, Pune, Maharashtra, India-412207. 

Sagar B Wankhede, Assistant Professor, Department of Quality Assurance Techniques, Dean of JSPM University School of Pharmaceutical Science, Wagholi, Pune, Maharashtra, India-412207.

Assistant Professor, Department of Quality Assurance Techniques, Dean of JSPM University School of Pharmaceutical Science, Wagholi, Pune, Maharashtra, India-412207. 

References

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Published

2026-01-15
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How to Cite

1.
Darade RR, Wankhede SB. Development and Validation of Stability Indicating RP-HPLC Method for the Estimation of Lasmiditan in tablet dosage form. J. Drug Delivery Ther. [Internet]. 2026 Jan. 15 [cited 2026 Jan. 19];16(1):36-42. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7516

Issue

Vol. 16 No. 1 (2026): Volume 16, Issue 1, Jan 2026

Section

Research

Copyright (c) 2026 Rahul Ramhari Darade, Sagar B Wankhede

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How to Cite

1.
Darade RR, Wankhede SB. Development and Validation of Stability Indicating RP-HPLC Method for the Estimation of Lasmiditan in tablet dosage form. J. Drug Delivery Ther. [Internet]. 2026 Jan. 15 [cited 2026 Jan. 19];16(1):36-42. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7516
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