IN VITRO ANTICANCER EFFECT OF ARTABOTRYS CRASSIFOLIUS HOOK.F. & THOMSON AGAINST HUMAN CARCINOMA CELL LINES
Abstract
The aim of the present study was to investigate the anticancer effects of crude extracts of Artabotrys crassifolius on the growth of human breast and colorectal carcinoma cell lines. The leaves and barks of Artabotrys crassifolius were extracted sequentially with hexane, chloroform and ethanol. The corresponding crude extracts obtained were then tested for their anticancer activity using MTT assay. Among the extracts studied, chloroform and hexane extracts of barks were found to possess the most potent anticancer activity which necessitates further isolation and characterisation of the bioactive compounds present in the respective extracts.
Keywords: Anticancer, Artabotrys crassifolius, Human carcinoma cell lines
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