Pharmacognostical Studies on Stems of Clerodendrum infortunatum L.

Authors

  • Joseph Jeenu Professor, Department of Pharmacognosy, Pushpagiri College of Pharmacy, Pushpagiri Medical Society, Tiruvalla, Kerala
  • Santhosh M Mathews Principal, Pushpagiri College of Pharmacy, Pushpagiri Medical Society, Tiruvalla, Kerala

Abstract

Clerodendrum infortunatum L. also known as Clerodendrum viscosum (Family Verbenaceae) is a perennial soft tomentose shrub that attains about 1m height consisting of light purple coloured or pinkish white flowers. It is widely used in traditional medicinal systems such as Ayurveda, Homeopathy and Unani due to its significant medicinal properties. It is commonly found in waste places of India, Burma and Bangladesh.

Aim: The present study was undertaken to lay down the pharmacognostical standards of stems of Clerodendrum infortunatum L. in order to validate / document its therapeutic benefits.

Materials and Methods: Stems of Clerodendrum infortunatum L. were subjected to pharmacognostical studies which include evaluation parameters such as histological study, microscopical study, fluorescence study, physicochemical analysis and phytochemical screening. Ethanolic and aqueous extracts were used for the physicochemical analysis and preliminary phytochemical screening

Results: Histological study revealed the presence and arrangement of various cells in the stem. Microscopical study revealed the presence of important characters such as covering trichomes, glandular trichomes, lignified fibres, wood elements, stone cells, medullary rays and calcium oxalate crystals. Preliminary phytochemical screening demonstrated the presence of phenolics, tannins, flavonoids, alkaloids, carbohydrates and glycosides.

Conclusion: The generated data could be significantly used to establish the pharmacognostic profile for the correct authentification, standardization and quality control of stems of Clerodendrum infortunatum L.

Keywords: Clerodendrum infortunatum, Verbenaceae, Bhandirah, Pharmacognostic evaluation, microscopy, macroscopy

Keywords:

Clerodendrum infortunatum, Verbenaceae, Bhandirah, Pharmacognostic evaluation, microscopy, macroscopy

DOI

https://doi.org/10.22270/jddt.v15i5.7033

Author Biographies

Joseph Jeenu , Professor, Department of Pharmacognosy, Pushpagiri College of Pharmacy, Pushpagiri Medical Society, Tiruvalla, Kerala

Professor, Department of Pharmacognosy, Pushpagiri College of Pharmacy, Pushpagiri Medical Society, Tiruvalla, Kerala

Santhosh M Mathews, Principal, Pushpagiri College of Pharmacy, Pushpagiri Medical Society, Tiruvalla, Kerala

Principal, Pushpagiri College of Pharmacy, Pushpagiri Medical Society, Tiruvalla, Kerala

References

1. Mohan Maruga Raja MK, Mishra SH. Comprehensive review of Clerodendrum phlomidis: A traditionally used bitter. Zhong Xi Yi Jie He Xue Bao. 2010;8:510-524. https://doi.org/10.3736/jcim20100602 PMid:20550872

2. Khatry N, Kundu J, Bachar SC, Mohammad NU, Kundu JK. Studies on antinociceptive, antiinflammatory and diuretic activities of methanol extract of the aerial parts of Clerodendron viscosum Vent. Dhaka Univ J Pharm Sci. 2005;5:63-66.

3. Rajurkar BM. Morphological study and medicinal importance of Clerodendrum infortunatum Gaertn.(Verbenaceae), Found in Tadoba National Park, India. J Pharm Res Health Care. 2010;2:216-220.

4. Shrivastava N, Patel T. Clerodendrum and healthcare: An overview. Med Aromat Plant Sci Biotechnol. 2007;1:142-150. https://doi.org/10.1007/s12010-007-0026-3 PMid:18025588

5.Haque MJ, Rouf MA, Jalil MA, Islam MB, Islam MR. Screening of phytochemical and biological potential of Clerodendron viscosum leaves extracts. Bangladesh J Sci Ind Res. 2010;45:381-6.

6.Gupta AK, Sharma M. Vol. 7. New Delhi: ICMR; 2008. Reviews on Indian Medicinal Plants; pp. 104-111.

7. Prashith Kekuda TR, Dhanya Shree VS, Saema Noorain GK, Sahana BK, Raghavendra HL, Ethnobotanical uses, phytochemistry and pharmacological activities of Clerodendrum infortunatum L. (Lamiaceae): A review, Journal of Drug Delivery and Therapeutics. 2019; 9(2):547-559 .

8. Brain K R and Turner T D, The practical evaluation of phytopharmaceuticals, Wright Scientechnica, Bristol, 1975, p.4-9.

9. Tandon N, Sharma P. Quality Standards of Indian Medicinal Plants Volume 16. Medicinal Plants Division, Indian Council of Medical Research, New DelhAi. 2018; 293-294.

10. Evans W C, Pharmacognosy, 15th edn, E Dinburg, London, 2002, 475, 101-105.

11. Kokate CK, Practical Pharmacognosy, 1st edn, Vallabh Prakashan, New Delhi, 1986, 111.

12. Singh P, Khosa RL, Srivastava S, Mishra G, Jha KK, Srivastava S, Sangeeta, Verma RK, Tahseen MA. Pharmacognostical study and establishment of quality parameters of aerial parts of Costus speciosus-a well known tropical folklore medicine. Asian Pac J Trop Biomed. 2014 Jun;4(6): 486-91.

13. Pharmacognostic and Phytochemical Studies of Leaves Psydrax horizontalis Schum. & Thonn (Rubiaceae). Pharmacognosy Journal, 2020;12(03):541-550. https://doi.org/10.5530/pj.2020.12.82

14. Adams SJ, Kuruvilla GR, Krishnamurthy K, et al. (2013). Pharmacognostic and phytochemical studies on Ayurvedic drugs Ativisha and Musta. Rev Brasileira Farmacog 23:398-409. 38https://doi.org/10.1590/S0102-695X2013005000040

15.Ministry of Health and Welfare. Indian pharmacopoeia. 4th ed. New Delhi: Ministry of Health and Welfare, Controller of Publications; 1996. pp. A53-A54.

16.Quality control of herbal drugs. Dr. Pulok K. Mukherjee. Horizons Pharmaceutical Publishers, 6th Edition. Pg: 186-201.

Published

2025-05-15
Statistics
Abstract Display: 1161
PDF Downloads: 1232
PDF Downloads: 17

How to Cite

1.
Jeenu J, Mathews SM. Pharmacognostical Studies on Stems of Clerodendrum infortunatum L. J. Drug Delivery Ther. [Internet]. 2025 May 15 [cited 2025 Oct. 25];15(5):17-22. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7033

How to Cite

1.
Jeenu J, Mathews SM. Pharmacognostical Studies on Stems of Clerodendrum infortunatum L. J. Drug Delivery Ther. [Internet]. 2025 May 15 [cited 2025 Oct. 25];15(5):17-22. Available from: https://www.jddtonline.info/index.php/jddt/article/view/7033