Exploring the Psycological Effects of Formoterol Fumarate and Budesonide Inhaler: A Case Study on Induced Depression
Abstract
A patient with a longstanding history of chronic obstructive pulmonary disease (COPD) presented with significant weight loss, loss of appetite, fatigue, and sleep disturbance persisting for 15 days, alongside a rapid weight loss of 15 kg in 10 days. Initial evaluations revealed bilateral pleural effusion, complicating her clinical picture. Despite no prior psychiatric history, a psychiatric evaluation indicated severe sleep disturbances, reduced food intake, and pronounced fatigue, leading to a diagnosis of depression. The patient's regular treatment included an inhaler containing formoterol fumarate and budesonide for 35 years. Notably, the inhaler’s long-term use may have contributed to her depressive symptoms. Emergency treatment involved intravenous administration of normal saline with multivitamins, pantoprazole to manage potential gastrointestinal complications, and a multivitamin and multimineral syrup. Psychiatric management included sertraline, an SSRI, to ameliorate depressive symptoms and zolpidem for sleep disturbances. This multidisciplinary approach resulted in significant improvement. Upon discharge, the patient was stable and prescribed a regimen including sertraline, pantoprazole, mirtazapine, zolpidem, and multivitamins to support her long-term recovery and well-being. The case underscores the potential for inhaler-induced depression in patients with COPD and the importance of a comprehensive treatment plan.
Keywords: Depression, Adverse event of inhaled drugs, chronic obstructive pulmonary disease, Weight loss
Keywords:
Depression , COPD, weightloss, adverse event of inhaler drugDOI
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Copyright (c) 2024 Subashini R, Priyadharshini R, Aishwarya S, Hema V
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