Therapeutic Drug Monitoring: A Review

Authors

  • Gyan Ranjan Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India, http://orcid.org/0009-0006-3335-4173
  • Faiqua Jamal Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India, http://orcid.org/0009-0001-5449-3862
  • Subhankar Das Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India, http://orcid.org/0000-0003-3753-5810
  • Vaibhav Gupta Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Abstract

Therapeutic drug monitoring (TDM) is well known for adjusting a patient’s medication dose such that the level of drug in their blood remains within a therapeutic range. TDM requires the concentration of a medication to be measured in a variety of physiological fluids.The method by which the medicine is manufactured also has an impact, because certain synthesised pharmaceuticals behave differently in the body than their licenced counterparts. TDM is one of the numerous areas where pharmacoeconomics is now being used. This is happening as both physicians and the general public grow increasingly worried about rising health-care expenses and the preparedness that has been identified as a consequence of using TDM. TDM helps in minimising risk while taking drugs like digoxin, aminoglycosides and various other drugs with narrow therapeutic index. TDM helps in identifying safer drug and dose of a drug by analysing the effects of the drug. TDM is used to ensure that the dosage of medication that you are taking is safe and effective. TDM is the clinical practice that monitors a drug’s or its metabolite’s concentration to guide personalized dosing with the goal of achieving a concentration target that is related to a desired treatment outcome.

Keywords: Therapeutic drug monitoring, vancomycin, aminoglycosides, digitalis, adverse effects.

Keywords:

Therapeutic drug monitoring, vancomycin, aminoglycosides, digitalis, adverse effects

DOI

https://doi.org/10.22270/jddt.v13i10.6251

Author Biographies

Gyan Ranjan, Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Faiqua Jamal, Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Subhankar Das, Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Vaibhav Gupta, Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

Department of Doctor of Pharmacy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur, Rajasthan, India,

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Published

15-10-2023
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How to Cite

1.
Ranjan G, Jamal F, Das S, Gupta V. Therapeutic Drug Monitoring: A Review. J. Drug Delivery Ther. [Internet]. 2023 Oct. 15 [cited 2025 Jun. 22];13(10):134-6. Available from: https://www.jddtonline.info/index.php/jddt/article/view/6251

How to Cite

1.
Ranjan G, Jamal F, Das S, Gupta V. Therapeutic Drug Monitoring: A Review. J. Drug Delivery Ther. [Internet]. 2023 Oct. 15 [cited 2025 Jun. 22];13(10):134-6. Available from: https://www.jddtonline.info/index.php/jddt/article/view/6251

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