A Pilot study on thyroid status, lipid profile creatine kinase in human cardiac patients
Abstract
Background: The progression of Coronary Heart Disease (CHD) is linked to a multitude of comorbidities, such as thyroid dysfunction, dyslipidemia. Objectives were to determine the thyroid and serum lipid profile, cholesterol, triglycerides and creatin kinase profile of CHD patients and to establish correlation between severity of cardiac disease with these two metabolic parameters.
Methods: This was a prospective study conducted among 55 CHD patients over 1 year admitted in the department of cardiology, General Government Hospital, Bikaner.
Results: There are 66% male and 36% female patients among the 55 study cases. Majority of the patients (54/55) exhibited higher T3 concentration, whereas one patient has low T4 value accompanied by 14 patients with high TSH value. Three patients have higher value of cholesterol with 17 patients of higher triglycerides levels. Among the patients eleven demonstrated higher creatine kinase values.
Conclusions: The numbers of patients increasing with decreasing T3 and increasing thyroid stimulating hormone (TSH) proportionate to the severity of the cardiac failure. In addition, hypothyroidism is becoming more common in people with chronic cardiac disease. Serum triglycerides, LDL and HDL levels rise statistically significantly in CHD patients.
Keywords: Dyslipidemia, CHD, Cholesterol, triglycerides, TMB.
Keywords:
Dyslipidemia, CHD, Cholesterol, triglycerides, TMBDOI
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