Evaluation of Extractive Value and In-Vitro antimicrobial potential of Curcuma longa using disk diffusion method

Authors

  • Arif Khan Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001
  • Arvind Singh Jadon Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001
  • Poonam Bhadauriya Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001

Abstract

The efficiency of turmeric fractions, such as petroleum ether, chloroform, benzene, methanol and aqueous were evaluated for their inhibitory effect on clinical and standard strains of pathogenic bacteria and fungus. The methanolic fraction of Curcuma longa rhizome had high potential to inhibit some pathogenic bacteria i.e. S. aureus to a greater degree than other fractions of Curcuma longa. In our study the results show that the different fractions (petroleum ether, methanol etc.) of Curcuma longa rhizome were more effective antimicrobial agents than the crude extract of Curcuma longa. Methanolic extract of curcuma longa was evaluated against gram positive and gram-negative bacteria. The bacteria isolates include Bacillus subtilis and Escherichia coli. Antimicrobial activities were estimated by Well diffusion method and antifungal activity was evaluated against Candida Albicans and Aspergillus Niger. The results were pointed as the methanol extract was more effective on both bacteria and fungus then water also similar effective on both bacteria and fungus but against Aspergillus Nigerit has outstand results. 

Keywords: Curcuma longa, Phytochemical, Antimicrobial, Free radical, Scavenging Potential

Keywords:

Curcuma longa, Phytochemical, Antimicrobial, Free radical, Scavenging Potential

DOI

https://doi.org/10.22270/jddt.v12i6-S.5842

Author Biographies

Arif Khan, Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001

Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001

Arvind Singh Jadon, Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001

Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001

Poonam Bhadauriya, Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001

Gurukul Institute of Pharmaceutical Science and Research, Gwalior, Madhya Pradesh, INDIA-474001

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Published

2022-12-15
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How to Cite

1.
Khan A, Jadon AS, Bhadauriya P. Evaluation of Extractive Value and In-Vitro antimicrobial potential of Curcuma longa using disk diffusion method. J. Drug Delivery Ther. [Internet]. 2022 Dec. 15 [cited 2025 Oct. 25];12(6-S):30-5. Available from: https://www.jddtonline.info/index.php/jddt/article/view/5842

How to Cite

1.
Khan A, Jadon AS, Bhadauriya P. Evaluation of Extractive Value and In-Vitro antimicrobial potential of Curcuma longa using disk diffusion method. J. Drug Delivery Ther. [Internet]. 2022 Dec. 15 [cited 2025 Oct. 25];12(6-S):30-5. Available from: https://www.jddtonline.info/index.php/jddt/article/view/5842