Evaluation of Extractive Value and In-Vitro antimicrobial potential of Curcuma longa using disk diffusion method
Abstract
The efficiency of turmeric fractions, such as petroleum ether, chloroform, benzene, methanol and aqueous were evaluated for their inhibitory effect on clinical and standard strains of pathogenic bacteria and fungus. The methanolic fraction of Curcuma longa rhizome had high potential to inhibit some pathogenic bacteria i.e. S. aureus to a greater degree than other fractions of Curcuma longa. In our study the results show that the different fractions (petroleum ether, methanol etc.) of Curcuma longa rhizome were more effective antimicrobial agents than the crude extract of Curcuma longa. Methanolic extract of curcuma longa was evaluated against gram positive and gram-negative bacteria. The bacteria isolates include Bacillus subtilis and Escherichia coli. Antimicrobial activities were estimated by Well diffusion method and antifungal activity was evaluated against Candida Albicans and Aspergillus Niger. The results were pointed as the methanol extract was more effective on both bacteria and fungus then water also similar effective on both bacteria and fungus but against Aspergillus Nigerit has outstand results.
Keywords: Curcuma longa, Phytochemical, Antimicrobial, Free radical, Scavenging Potential
Keywords:
Curcuma longa, Phytochemical, Antimicrobial, Free radical, Scavenging PotentialDOI
https://doi.org/10.22270/jddt.v12i6-S.5842References
Ferrero-Miliani L, Nielsen O, Andersen P, Girardin S. Chronic inflammation: importance of NOD2 and NALP3 in interleukin-1β generation, Clin Exp Immunol. 2007; 147:227-235. https://doi.org/10.1111/j.1365-2249.2006.03261.x
Takeuchi O, Akira S. Pattern Recognition Receptors and Inflammation. Cell, 2010; 140:805-20. https://doi.org/10.1016/j.cell.2010.01.022
Abdullahi A.A. Trends and challenges of traditional medicine in Africa. Afr. J. Tradit. Complement. Altern. Med. 2011; 8:115-123. https://doi.org/10.4314/ajtcam.v8i5S.5
Parasuraman S., Thing G.S., Dhanaraj S.A. Polyherbal formation: Concept of ayurveda. Pharmacogn. Rev. 2014; 8:73-80. https://doi.org/10.4103/0973-7847.134229
Duke J. Turmeric-The Genus Curcuma, Medicinal and Aromatic Plants-Industrial Profiles. Eco Bot. 2007; 61(4):397-398. https://doi.org/10.1663/0013-0001(2007)61[397b:TGCMAA]2.0.CO;2
Araujo C. C, Leon L. L. Biological activities of Curcuma longa L. Mem Inst Oswaldo Cruz. 2001; 96:723-8. https://doi.org/10.1590/S0074-02762001000500026
Tilak J. C, Banerjee M, Mohan H, Devasagayam T. P. Antioxidant availability of turmeric in relation to its medicinal and culinary uses. Phytother Res. 2004; 18:798-804. https://doi.org/10.1002/ptr.1553
Parasuraman S., Thing G.S., Dhanaraj S.A. Polyherbal formation: Concept of ayurveda. Pharmacogn. Rev. 2014; 8:73-80. https://doi.org/10.4103/0973-7847.134229
Wanda C Reygaert. An overview of the antimicrobial resistance mechanisms of bacteria, AIMS microbial .2018; 4(3):482-501. https://doi.org/10.3934/microbiol.2018.3.482
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