Effect of Consuming Different Varieties of Bambara Groundnut (Vigna subterranea) Seeds on Glycaemia and Lipid Profile of Diabetic and Non-Diabetic Rats
Abstract
Background: Bambara groundnut seed is reported to possess high fibre and good nutritional content, and is locally used as a daily dietary therapy by diabetic patients in northern Nigeria. The plant seeds are of different varieties and whether the antidiabetic effect may vary with the varieties is largely unknown. This has prompted the current study to investigate effect of consuming different varieties of Bambara groundnut seeds on glycaemia and lipid profile of diabetic and non-diabetic rats.
Materials and Methods: Bambara groundnut seed’s varieties were processed into flour and use in formulating feeds which were given to diabetic and non-diabetic rats as follows; group A (ALK01 feed), group B (ALK02 feed), group C (ALK03 feed), group D (ALK04 feed), group E (Basal feed), and group F (Normal animal’s feed) for 28 days during which blood glucose and weights were measured weekly while lipid profile was assayed at the end of the study.
Results: The result of the study showed continuous increase in glycemic levels for diabetic rats fed basal and normal feeds compared to those fed plant seed formulated feeds. While, glycemic levels for non-diabetic rats fed plant seed formulated feeds, normal or basal feeds remain within normal range. The lipid components of diabetic rats fed basal and normal feeds were elevated and are significantly different (P<.05) from those fed plant seed formulated feeds.
Conclusion: The study concluded that consumption of different varieties of Bambara groundnut seed could ameliorate hyperglycemia and hyperlipidemia by a variety dependent manner.
Keywords: Bambara groundnut, seed varieties, effect, glycaemia, lipid profile, rats
Keywords:
Bambara groundnut, seed varieties, effect, glycaemia, lipid profile, ratsDOI
https://doi.org/10.22270/jddt.v11i5-S.5011References
Nwajiobi OJ, Ogbunugafor HA, Ezenwelu CO, Oche B, Nwokeke CC and Ogoke JT. The effect of a combination of D. dumetorum and V. subterranea feed on blood glucose level and serum lipid profile in alloxan-induced diabetic rats. Inter J Agri Biosci, 2016; 5:109-112.
Udenta EA, Obizoba IC, Oguntibeju OO. Antidiabetic effects of Nigerian indigenous plant foods/diets. Antioxidant -Antidiabetic Agents and Human Health. 2014; 3. doi.10.5772/ 57240.
Mann JI. Diet and diabetes. Diabetologia, 1980; 18:89-95. doi.10.1007/BF00290 483 11. https://doi.org/10.1007/BF00290483
Little D. Non-pharmacological management of diabetes: The role of diet and exercise. Geriatrics Aging. 2003; 6:27-9.
Michael JF. Diabetes treatment, part 1: Diet and exercise. Clin. Diabetes., 2007; 25:105-9. https://doi.org/10.2337/diaclin.25.3.105
Wolever TMS, Katzman-Relle L, Jenkins AL, et al. Glycaemic index of 102 complex carbohydrate foods in patients with diabetes. Nutr. Res. 1994; 14:651-69. doi.10.1016/S02715317(05)80201-5 https://doi.org/10.1016/S0271-5317(05)80201-5
Jenkins DJ, Wolever TM, Taylor RH. Glycaemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin. Nutr., 1981,34:362-6. https://doi.org/10.1093/ajcn/34.3.362
Thomas D, Elliott EJ, Baur. Low glycaemic index or low glycaemic load diets for overweight and obesity. Cochrane Database Syst. Rev., 2007; 3:CD005105. https://doi.org/10.1002/14651858.CD005105.pub2
Ohwovoriole AE and Johnson TO. Which Nigerian food for the diabetic? Nig. J. Nutr. Sci., 1984; 5:59-62.
Oboh H, Osagie A, Omotosho A. Glycaemic response of some boiled legumes commonly eaten in Nigeria. Diabetol. Croatica., 2010; 39:125-131.
Olarinoye JK, Ano- Edwards GH, Alade I. Knowledge and practice of medical nutrition therapy by diabetes care givers in Ilorin, Nigeria. Nig. Med. Pract., 2007; 51:55-8. https://doi.org/10.4314/nmp.v51i4.28842
Olanipekun BF, Otunola ET, Adejuyitan JA, Adeyanju . Proximate and fatty composition of bambara groundnut (Voandzeia subterranea) as Influenced by fermentation with a combination of Rhizopus oligosporous and R. nigricans. Transnat J Sci Technol., 2012; 2:107-110.
Bambara groundnuts (Vigna subterranean): Production guideline for Bambara groundnuts. Directorate agricultural information services, department of agriculture, forestry and fisheries, Republic of South Afric. 2011; 110. Available: https://www.nda.agric.za/docs/Brochures/P rodguideBambara.pdf
National Research Council (NRC, 2006). Lost crops of Africa: Volume II: Vegetables. http://www.nap.edu/ catalog/11763.html.
Oyenuga V.A,. Nigerian Foods and Feeding-Stuffs. Their Chemistry and Nutritive Value,. Ibadan University Press, 1968, Ibadan.
Adedayo OA and Ganiyu O. Attenuation of oxidative stress and hepatic damage by some fermented tropical legume condiments diets in streptozotocin-induced diabetes in rats. Asian Pacific J Trop Med., 2012; 5:692-697. https://doi.org/10.1016/S1995-7645(12)60108-4
Mohammed A and Mhya DH. Effects of Consuming Different Varieties of Bambara Nut (Vigna subterranea) Seeds on Liver and Kidney of Diabetic and Non-diabetic Subject. Journal of Advances in Biology & Biotechnology, 2021; 24:25-35. doi: 10.9734/JABB/2021/v24i630219. https://doi.org/10.9734/jabb/2021/v24i630219
Neelesh M, Sanjay J, and Sapna M,. Antidiabetic Potential of Medicinal Plants. Acta Poloniae Pharmaceutica-Drug Res, 2010; 67: 113-118
Olubunmi A, Oluwatosin A, Dare A. Antioxidative potentials of cooked bambara groundnut based diet (Vigna subterranean) on lipid peroxidation status in pretreated alloxan induced diabetic rats. World Journal of Pharmacy and Pharmaceutical Sciences., 2017; 6:62-76. https://doi.org/10.20959/wjpps20174-8891
Fossati P and Prencipe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin. Chem., 1982; 28:2077-2080. https://doi.org/10.1093/clinchem/28.10.2077
Roeschlau P, Bernt E, Gruber W. Enzymatic determination of total cholesterol in serum. Z. Klin. Chem. Klin. Biochem., 1974; 12:226-226.
Lopes-Virella MF, Stone P, Ellis S, Colwell JA. Cholesterol determination in highdensity lipoproteins separated by three different methods. Clin. Chem., 1977; 23:882-884. https://doi.org/10.1093/clinchem/23.5.882
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifug. Clin. Chem., 1972; 18:499502. https://doi.org/10.1093/clinchem/18.6.499
Clark P.M.S. and Hales C.N. How to measure plasma insulin. Diabetes/Metab. Rev., 1994; 10(1):79-90. https://doi.org/10.1002/dmr.5610100203
Duncan BD. Multiple range test for correlated and heteroscedastic means. Biometrics., 1957; 13:359-364 https://doi.org/10.2307/2527799
Mohammed A and Mhya DH. Evaluation of phytochemical constituents, proximate contents and glycemic index of bambara groundnut (Vigna subterranea L. Verdc) varieties grown in Northeastern Nigeria. Afri J Biochemistry Res., 2021; 15:22-27. DOI: 10.5897/AJBR2021.1120
Bastaki S. Diabetes mellitus and its treatment. Int. J. Diabetes Metab., 2005; 13: 111-134 https://doi.org/10.1159/000497580
Nesto RW. Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndrome. Am J Cardiovasc Care, 2005; 5:379-387. https://doi.org/10.2165/00129784-200505060-00005
Granner DK. Hormones of the pancreas and gastrointestinal tract. In: Murray RK, DK Granner, PA Mayes, VW Rodwel (eds), 1996. Harper's Biochemistry, ed 24, Connecticut, USA, Appleton and Lange, 586-587
Okpuzor J, Ogbunugafor HA, Okafor U and Sofidiya MO. Identification of protein types in Bambara groundnut seeds: perspectives for dietary protein supply in developing countries. EXCLI J, 2010; 9:17-28.
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