FLOATING DRUG DELIVERY SYSTEM: A INNOVATIVE APPROACH
Abstract
The current Pharmaceutical scenario focuses on the development of sustained drug delivery systems to achieve required therapeutic concentration with less amount of dose. Several approaches are currently utilized in the prolongation of the gastric residence time including floating drug delivery systems, swelling and expending system, polymeric bio-adhesive systems, high density systems, modified-shape systems and other delayed gastric emptying devices. From the formulation and technological point of view, the floating drug delivery system is comparatively easy and logical approach. Floating drug delivery system is one amongst the GRDFs used to achieve prolonged gastric residence time (GRT). In this review the methods of evaluation of various floating dosage forms and applications of these systems are summarized.
Keywords: Floating drug delivery system (FDDS), Gastric residence time (GRT), Buoyancy
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DOI
https://doi.org/10.22270/jddt.v2i6.315
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