Formulation Development and Evaluation of Gastroretentive Delivery System (Microspheres) Using Natural Polymer
Abstract
Microspheres are novel drug delivery approach to control release of pharmacologically active ingredient as per patient need. Natural polymers like fenugreek mucilage are cheap, biodegradable and have been proved safe for pharmaceutical formulation. Higher loading efficiency was observed for all the formulations and also the drug release was observed for the period of 12 hours. Thus, the simvastatin microsphere using fenugreek mucilage showed promising results in retarding the drug release. It can be concluded from whole study that due to the formation of polymeric network system or other active moiety can be easily entrapped with the matrix and hydration and swelling of natural polymer controlled their release pattern
DOI
https://doi.org/10.22270/jddt.v9i4.3079Published
2019-07-15
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Rai A, Malviya RK, Patidar D, Sharma K, Raj V. Formulation Development and Evaluation of Gastroretentive Delivery System (Microspheres) Using Natural Polymer. J. Drug Delivery Ther. [Internet]. 2019 Jul. 15 [cited 2025 Nov. 6];9(4):496-503. Available from: https://www.jddtonline.info/index.php/jddt/article/view/3079
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How to Cite
1.
Rai A, Malviya RK, Patidar D, Sharma K, Raj V. Formulation Development and Evaluation of Gastroretentive Delivery System (Microspheres) Using Natural Polymer. J. Drug Delivery Ther. [Internet]. 2019 Jul. 15 [cited 2025 Nov. 6];9(4):496-503. Available from: https://www.jddtonline.info/index.php/jddt/article/view/3079
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