Antibiotic Resistance in Malaysia, and its Public Health Implications
Abstract
The World Health Organization (WHO) notes high-rates of resistance among bacteria associated with common illness in all the WHO-regions - both hospital-acquired and community-acquired (WHO 2014). An estimated 2 million cases of antibiotic-resistance are reported in the US annually, causing 23,000 deaths. With reference to such, the US CDC states that about 30% of the total-annual 150 million prescriptions for antibiotics is not justified. There is a need for greater prudence in the use involving joint-efforts in surveillance, public health awareness additionally, and in formulating clear policies on procurement and prudent use.
Keywords: Antibiotic Resistance, Public Health, prescriptions
DOI
https://doi.org/10.22270/jddt.v9i2.2427References
Meer Ahmad Meera. Antibiotic-prescription, dispensing and the public-health implications of resistance. Berita MMA Vol 48 No 3. March 2018
WHO (2014). Antimicrobial resistance: Global report on surveillance. World Health Organization.
CDC (2013). Antibiotic resistance threats in the United States, 2013. US Department for Health and Human Services. Centers for Disease Control.
Gerardo Alvarez-Uria, Sumanth Gandra, Siddhartha Mandal and Ramanan Laxminarayan. Global forecast of antimicrobial resistance in invasive isolates of Escherichia coli and Klebsiella pneumonia. Int J Infect Dis. 2018 Mar; 68: 50–53. doi: 10.1016/j.ijid.2018.01.011
Mario Tumbarello, Teresa Spanu, Rossella Di Bidino, Marco Marchetti, Matteo Ruggeri, Enrico Maria Trecarichi, Gennaro De Pascale, Enrica Maria Proli, Roberto Cauda, Americo Cicchetti and Giovanni Fadda. Costs of Bloodstream Infections Caused by Escherichia coli and Influence of Extended-Spectrum-β-Lactamase Production and Inadequate Initial Antibiotic Therapy. Antimicrob Agents Chemother. 2010 Oct; 54(10): 4085–4091. doi: 10.1128/AAC.00143-10
Kim L, McGee L, Tomczyk S, Beall B. Biological and Epidemiological Features of Antibiotic-Resistant Streptococcus pneumoniae in Pre- and Post-Conjugate Vaccine Eras: a United States Perspective. Clin Microbiol Rev. 2016 Jul;29(3):525-52. doi: 10.1128/CMR.00058-15.
Kariuki S, Gordon MA, Feasey N and Parry CM. Antimicrobial resistance and management of invasive Salmonella disease. Vaccine. 2015 Jun 19; 33(0 3): C21–C29. doi: 10.1016/j.vaccine.2015.03.102
Gebrekidan A, Dejene TA, Kahsay G, Wasihun AG. Prevalence and antimicrobial susceptibility patterns of Shigella among acute diarrheal outpatients in Mekelle hospital, Northern Ethiopia. BMC Res Notes. 2015 Oct 28;8:611. doi: 10.1186/s13104-015-1606-x.
Tapsall JW, Ndowa F, Lewis DA, Unemo M. Meeting the public health challenge of multidrug- and extensively drug-resistant Neisseria gonorrhoeae. Expert Rev Anti Infect Ther. 2009 Sep;7(7):821-34. doi: 10.1586/eri.09.63
Lahra MM, Lo YR, Whiley DM. Gonococcal antimicrobial resistance in the Western Pacific Region. Sex Transm Infect. 2013 Dec;89 Suppl 4:iv19-23. doi: 10.1136/sextrans-2012-050906.
Gagneux S, Long CD, Small PM, Tran Van, Schoolnik GK, Bohannan BJM. The Competitive Cost of Antibiotic Resistance in Mycobacterium tuberculosis. Science 312, 1944 (2006). DOI: 10.1126/science.1124410
Gillespie SH. Evolution of Drug Resistance in Mycobacterium tuberculosis: Clinical and Molecular Perspective. Antimicrob Agents Chemother. 2002 Feb; 46(2): 267–274. doi: 10.1128/AAC.46.2.267-274.2002
White NJ. Antimalarial drug resistance. J Clin Invest. 2004 Apr 15; 113(8): 1084–1092. doi: 10.1172/JCI200421682
Tang MW and Shafer RW. HIV-1 Antiretroviral Resistance: Scientific Principles and Clinical Applications. Drugs. 2012; 72(9): e1–e25. doi: 10.2165/11633630-000000000-00000
Whaley SG, Berkow EL, Rybak JM et al. Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species. Front Microbiol. 2016; 7: 2173. doi: 10.3389/fmicb.2016.02173
Norazida AR, Cheong LT, Sheamini S. Antibiotic prescribing in public and private practice: a cross-sectional study in primary care clinics in Malaysia. BMC Infect Dis. 2016; 16: 208. Published online 2016 May 17. doi: 10.1186/s12879-016-1530-2 [PMCID: PMC4869350]
Tan WL, Siti Rahmah, Shahfini I, Zuraidah A. Knowledge, attitude and practices of antibiotic prescribing among medical officers of public health services in the state of Kedah, Malaysia. Med J Malaysia. Vol 70 No 5. 2015
Qamar M, Sheikh Abdullah NH, Khan J, Mahmud A, Ahmad A. Knowledge and attitude towards antibiotic usage among general public in Shah Alam, Malaysia. UK J Pharm Biosci 2 (6), 60-66
Bell BG, Schellevis F, Stobberingh E, Goossens H, Pringle M. A systematic review and meta-analysis of the effects of antibiotic consumption on antibiotic resistance. BMC Infect Dis. 2014 Jan 9;14:13. doi: 10.1186/1471-2334-14-13.
Woolhouse M, Waugh C, Perry MR and Nair H. Global disease burden due to antibiotic resistance – state of the evidence. J Glob Health. 2016 Jun; 6(1): 010306. doi: 10.7189/jogh.06.010306
CDC. Antibiotic / Antimicrobial Resistance (AR / AMR).. U.S. Department of Health & Human Services. Centers for Disease Control and Prevention. 2018. https://www.cdc.gov/drugresistance/index.html
Cosgrove SE. The Relationship between Antimicrobial Resistance and Patient Outcomes: Mortality, Length of Hospital Stay, and Health Care Costs. Clinical Infectious Diseases 2006; 42:S82–9
Naylor NR, Rifat A, Zhu N, Kulasabanathan K, Silva S, Chatterjee A, Knight GM and Robotham JV. Estimating the burden of antimicrobial resistance: a systematic literature review. Antimicrob Resist Infect Control. 2018; 7: 58. doi: 10.1186/s13756-018-0336-y
Thaden JT, Li Y, Ruffin F, Maskarinec SA, Hill-Rorie JM, Wanda LC, Reed SD, Fowler VG, Jr. Increased Costs Associated with Bloodstream Infections Caused by Multidrug-Resistant Gram-Negative Bacteria Are Due Primarily to Patients with Hospital-Acquired Infections. American Society for Microbiology Journals. 2017. doi.org/10.1128/AAC.01709-16
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