NOOTROPICS AGENTS: PHARMACEUTICAL ASPECT, COMMON EXAMPLES AND THEIR APPLICATIONS
Abstract
Nootropics compounds are one of the important categories of medicinal agents act as cognitive enhancers and neuroprotective. These agents mainly used to improve memory related functioning of brain. Nootropic compounds exhibited various neural activities and boost functioning of central nervous system including improvement of intellectual, memory and learning capacity. These agents also offer significant relief in various neurodegenerative disorders such as parkinson disease and alzheimer disease. Drugs, nutraceuticals, supplements and functional foods may be used as nootropics agents to enhance concentration and memory. Various synthetic & semi synthetic agents, material from natural origin such as; herbs, animal products and minerals may also act as potent nootropic agents. This article presented a pharmaceutical consideration of nootropic agents in a view to explore this area for future perspective.
Keywords: Nootropics, Memory, Cognitive, Brain, Neuroprotective
DOI
https://doi.org/10.22270/jddt.v8i5-s.1940References
Bhanumathy M, Harish MS, Shivaprasad HN, Sushma G Nootropic activity of Celastrus paniculatus seed. Pharm. Biol. 2010; 48(3):324-327.
Cook L, Weidley E Behavioural effects of some psycho-pharmacological agents. Ann. NY. Acad. Sci. 1957; 66:740-752.
Giurage C. The “nootropic” approach to the integrative activity of the brain. Cond. Reflex. 1973; 8(2):108-115.
Jakka Al A study on nootropic activity of Celastrus paniculata wild whole plant methanolic extract in rats. Asian. J. Pharm. Clin. Res. 2016; 9(1):336-341.
Schever K, Rostock A, Bartsch P, Muller WK. Piracetam improved cognitive performance by restoring neurochemical deficits of the aged rat brain. Pharmacopsychiatry 1999; 32 Suppl 1:10-6.
Michael S. (2006) The Ethical Brain: The Science of Our Moral Dilemmas (P.S.). N.Y: Harper Perennial. p. 184.
Paula J (2008). The medical basis of psychiatry. Totowa, NJ: Humana Press. ISBN 1-58829-917-1.
Gattu M, Boss KL, Terry A V, Buccafusco JJ. (1997) Reversal of scopolamine-induced deficits in navigational memory performance by the seed oil of Celastrus paniculatus. Pharmacol Biochem Behav, 57(4): 793-799.
Malik J, Karan M, Dogra R. (2017) Ameliorating effect of Celastrus paniculatus standardized extract and its fractions on 3-nitropropionic acid induced neuronal damage in rats: possible antioxidant mechanism. Pharm Biol, 55(1): 980-990.
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