SOFT CHEWABLE DRUG DELIVERY SYSTEM: ORAL MEDICATED JELLY AND SOFT CHEW
Abstract
Oral route is most commonly used for administration of medicament since they are economical, easy to administer, & high patient acceptance. Due to difficulty in administration of therapeutic agents to dysphagia patients it becomes necessary to develop a formulation in order to overcome such inconvenience. Jellies are semisolid dosage form they are transparent, non greasy, & can be used internally as well as externally. Its matrix include large amount of water & they resemble to mucilage but possess jelly like consistency. Advantages of chewable formulation are that it does not require water for ingestion, aesthetic appearance, and good texture. Soft chew is solid, single dose formulation. It is used as acute medication since it is mobile drug delivery systems. They are formulated using heating & congealing technique. It serves as novel dosage form with wide applications in pharmaceuticals, nutraceuticals and over the counter medicines
Keywords: Jellies, Soft chew, Nutraceuticals
DOI
https://doi.org/10.22270/jddt.v8i4.1784References
Mishra B, Sharma G, Investigation of organoleptic characteristics in the development of soft chews of calcium carbonate as mineral supplement,Yakugaku Zasshi, 2009; 129(12):1537-1544.
Raja Manali M, Dhiren P, Oral medicated jelly: a recent advancement in formulation, An international journal of pharmaceutical sciences, 2016; 7(2):13-20.
Wikipedia contributors. Alginic acid. Wikipedia, The Free Encyclopedia. May 21, 2018, 02:49 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Alginic_acid&oldid=842229245.
Wikipedia contributors. Pectin. Wikipedia, The Free Encyclopedia. June 15, 2018, 14:21 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Pectin&oldid=845988473.
Wikipedia contributors. Tragacanth. Wikipedia, The Free Encyclopedia. June 6, 2018, 21:26 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Tragacanth&oldid=844744223.
Wikipedia contributors. Gelatin. Wikipedia, The Free Encyclopedia. June 6, 2018, 10:16 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Gelatin&oldid=844670188.
Wikipedia contributors. Xanthan gum. Wikipedia, The Free Encyclopedia. June 14, 2018, 15:11 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Xanthan_gum&oldid=845848216.
Wikipedia contributors. Carboxymethyl cellulose. Wikipedia, The Free Encyclopedia. June 13, 2018,0:42UTC.Availableat: https://en.wikipedia.org/w/index.php?title=Carboxymethyl_cellulose&oldid=845671169
Wikipedia contributors. Agar. Wikipedia, The Free Encyclopedia. June 20, 2018, 17:55 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Agar&oldid=846753815.
Wikipedia contributors. Carrageenan. Wikipedia, The Free Encyclopedia. June 25, 2018, 20:24 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Carrageenan&oldid=847502464.
Debojyoti B, organoleptic agents: adaptability, acceptability and palatability in formulations to make it lucrative. World Journal of Pharmaceutical Research .2015; (4):1573-1586.
Renu, Jyoti D, Chewable Tablets: A Comprehensive Review, The Pharma Innovation Journal, 2015; 4(5):100-105.
Eric D, Frank T, Grant E, Sweeteners: discovery, molecular design, and chemoreception, Food/Nahrung, 1991; 35(10):1046
Wikipedia contributors. Preservative. Wikipedia, The Free Encyclopedia. June 12, 2018, 05:30 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Preservative&oldid=845498444.
Javed H,Shah S,Formulation and Evaluation of Taste Masked Doxycycline HCl Medicated Jelly, Der Pharmacia Sinica, 2017; 8(2):33-39
Pundir S, Verma AM, Oral disintegrating preparation - medicated chewing gum, Pharma Utility, 2014, Volume 8.
Wikipedia contributors. Candy making. Wikipedia, The Free Encyclopedia. April 30, 2018, 14:15 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Candy_making&oldid=838979532.
Available at: http://www.chemistryindustry.biz/emulsifiers.html
Wikipedia contributors. Polysorbate 80. Wikipedia, The Free Encyclopedia. May 16, 2018, 08:37 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Polysorbate_80&oldid=841509853.
Wikipedia contributors. Sorbitan monostearate. Wikipedia, The Free Encyclopedia. May 24, 2018, Available at: https://en.wikipedia.org/w/index.php?title=Sorbitan_monostearate&oldid=842777923.
Rohm H, Schaper C, Zahn S, Interesterified fats in chocolate and bakery products: A concise review,LWT - Food Science and Technology, 2018; 87:379-384.
Wikipedia contributors. Condensed milk. Wikipedia, The Free Encyclopedia. June 21, 2018, 17:14UTC.Availablehttps://en.wikipedia.org/w/index.php?title=Condensed_milk&oldid=846914233.
Wikipedia contributors. Cream. Wikipedia, The Free Encyclopedia. June 8, 2018, 03:43 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Cream&oldid=844924476.
Nanda AR, Garg KS, An update on taste masking technologies for Oral pharmaceuticals, Indian Journal Pharma. sci. 2002; 64(1).
Available at http://www.foodadditivesworld.com/
Wikipedia contributors. Sodium benzoate. Wikipedia, The Free Encyclopedia. June 13, 2018, 05:05UTC.Availableathttps://en.wikipedia.org/w/index.php?title=Sodium_benzoate&oldid=845642500.
Wikipedia contributors. Methylparaben. Wikipedia, The Free Encyclopedia. June 16, 2018, 16:01 UTC. Available at: https://en.wikipedia.org/w/index.php?title=Methylparaben&oldid=846138187
Wikipedia contributors. Propylparaben. Wikipedia, The Free Encyclopedia. March 29, 2018, 06:40UTC.Availableat: https://en.wikipedia.org/w/index.php?title=Propylparaben&oldid=833017551.
Published
Abstract Display: 3456 
PDF Downloads: 3424 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.