SIMULTANEOUS STIMATION OF ASPIRIN AND OMEPRAZOLE (Y0SPRALA) IN BULK BY UV-SPECTROSCOPY
Abstract
In India, there are roughly 30 million heart patients and two lakh surgeries are being performed every year. YOSPRALA-a new emerging drug approved by USFDA in September 2016 to treat Ischemic stroke, prophylaxis and gastric ulcer prophylaxis. The active ingredients present are Aspirin and Omeprazole.Hence ana attempt is made to develop a new analytical method for Simultaneous estimation of Aspirin and Omeprazole using methanol as solvent The Absorption maxima of Aspirin and Omeprazole was at 224nm and 251.8nm respectively. Linearity range for aspirin was 0.5-25µg/ml with regression co-efficient-099 and omeprazole was 1-8µg/ml with regression coefficient 0.992. The method was validated for precision and %RSD was less than 1.5% for both aspirin and omeprazole. The proposed method was statistically validated for standard deviation, relative standard deviation.coefficient of variance and the results were within the limits. Hence the above method was simple, cost effective, robust and can be used for routine analysis in in pharmaceutical preparations.
Keywords: Yosprala, Aspirin and Omeprazole, UV spectroscopy.DOI
https://doi.org/10.22270/jddt.v7i3.1421Published
Abstract Display: 1369 
PDF Downloads: 1264 How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
How to Cite
.