CONSEQUENCE OF CALENDULA OIL ON THE IN- VITRO PERCUTANEOUS ABSORPTION OF DICLOFENAC SODIUM
Abstract
Terpenes are widely used as penetration enhancers in transdermal drug delivery system. Calendula oil also contains different terpenes. The enhancing effect of calendula oil on the in- vitro percutaneous absorption of diclofenac sodium (DFS) from carbopol gels containing propylene glycol was investigated. Permeation experiments were performed on artificial skin membrane. The permeation effect of calendula oil on DFS is compared with geraniol and menthol (mild accelerants) . The enhancing effect of calendula oil was found to be more as compared with geraniol and menthol. However, although the addition of calendula oil increased DFS flux; diffusional lag times were longer than for the control gelDOI
https://doi.org/10.22270/jddt.v2i3.139
Published
2012-05-14
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Bodhankar M, Kavade V, Patil A. CONSEQUENCE OF CALENDULA OIL ON THE IN- VITRO PERCUTANEOUS ABSORPTION OF DICLOFENAC SODIUM. J. Drug Delivery Ther. [Internet]. 2012 May 14 [cited 2026 Apr. 30];2(3). Available from: https://www.jddtonline.info/index.php/jddt/article/view/139
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Research
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How to Cite
1.
Bodhankar M, Kavade V, Patil A. CONSEQUENCE OF CALENDULA OIL ON THE IN- VITRO PERCUTANEOUS ABSORPTION OF DICLOFENAC SODIUM. J. Drug Delivery Ther. [Internet]. 2012 May 14 [cited 2026 Apr. 30];2(3). Available from: https://www.jddtonline.info/index.php/jddt/article/view/139
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