EVALUATION OF ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ETHANOLIC POLYHERBAL EXTRACT

  • N Deattu Department of Pharmaceutics, College of Pharmacy, Madras Medical College, Chennai-03
  • L Suseela Jamia Salafia College of Pharmacy, Calicut, Kerala
  • N Narayanan Jaya College of Pharmacy, Tiruninravur, Chennai.

Abstract

Antimicrobial activity of an ethanolic polyherbal extract was examined against the bacterial strains, Escherichia coli, Proteus mirabilis, Gardnerella vaginalis and Pseudomonas aeruginosa and the fungal strains, Candida albicans and Aspergillus niger using disc diffusion method. The polyherbal extract was prepared from the combined ethanolic extracts of Saraca indica, Symplocos racemosa, Hemidesmus indicus, Aloe vera, Asteracantha longifolia, Erythrina indica and Tribulus terrestris. Antibacterial activity was determined using Mueller Hinton Agar (MHA) medium and antifungal activity was studied using Potato dextrose agar (PDA) medium. The polyherbal extract showed significant antimicrobial activity against the tested microorganisms. The  minimum inhibitory concentration (MIC) value was also determined which was found to be 1 mg/ml against the selected microorganisms.

Key Words: Antibacterial activity, antifungal activity, polyherbal extract, minimum inhibitory concentration

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1.
Deattu N, Suseela L, Narayanan N. EVALUATION OF ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ETHANOLIC POLYHERBAL EXTRACT. JDDT [Internet]. 11Nov.2012 [cited 29Nov.2021];2(6). Available from: http://www.jddtonline.info/index.php/jddt/article/view/321