Preliminary Phytochemical Screening and Antimicrobial Activity of the Hydroethanolic Extract of the Fruits of Solanum torvum (Swartz) (Solanaceae) Use as Vegetable in Togo
Abstract
The fruits of Solanum torvum (Swartz), a vegetable-fruit, are used in traditional medicine in Togo in the treatment of infectious diseases and as an anti-anemic. This study then focused on the antimicrobial activity assessment of the hydroethanolic extract of these fruits in the interest of contributing to the valorization of this Togolese flora’s species. A hydroethanolic extraction (50 % - 50 %: v/v) was performed followed by preliminary phytochemical tests. Antimicrobial activity was determined on fourteen bacterial strains using the agar diffusion method. Qualitative phytochemical screening revealed the presence of alkaloids, reducing compounds, tannins, cardiac glycosides, flavonoids, coumarins, triterpenes, saponins, total carbohydrates and free quinones. The extract was active on the reference strains of S. aureus, E. coli, S. pneumoniae and P. aeruginosa. However, this activity was only observed on clinical strains of S. pneumoniae and P. aeruginosa. The extract showed MICs of 25 and 50 mg/ml and BMCs of 50 and 100 mg/ml respectively for S. pneumoniae and P. aeruginosa. The MBC/MIC ratio for these two strains was 2. These fruits would then have bacteriostatic activity on S. pneumoniae and P. aeruginosa. The antibacterial properties of the extract on these germs could justify the use of this plant in traditional medicine for the treatment of certain bacterial infections.
Keywords: Solanum torvum, fruits, phytochemical compounds, antimicrobial activity
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2. Saffidine K., Analytical and biological study of the flavonoîdes extracted from Carthamus caeruleus L. and de Plantago major L. Available from: https://eng.univ-setif.dz. 2015. p 132AD. In french
3. Bene K., Djeneb C., Fofie N. B., Kanga Y., Yapi A., Yapo Y., Ambre S., Zirihi G. Ethnobotanic study of the medicinal plants used in the Department of Transua, District of Zanzan (Côte d’Ivoire). Journal of Animal and Plant Sciences, 2016; 27:4230-4250. In french
4. Himour S., Yahia A., Hakima B., Bellebcir L., Phytochimic study of sheets of Olea europaea L. var Chemlel of Algeria. Journal of Bioresources Valorization, 2016; 1(1):34-38. In french
5. Dominique A. L. M., Jean-Marc Z. B. G., Kouadio B., Noël Z. G., Étude Ethnobotanique et Screening Phytochimique de Quelques Ptéridophytes de la Forêt Classée de Yapo-Abbé (Côte d’Ivoire). Eur Sci J ESJ. 2018; 14(33):173-173. doi:10.19044/esj
6. Mahesh G., Phytochemical Evaluation, Antiinflamatory Activity, And Determination of Bioactive Components from leaves of Mussaenda Frondosa. Indo Am J Pharm Sci. 2017; 04(09):3333-3341. doi :10.5281/zenodo.998165
7. Souley K. M, Adamou R., Sawadogo J., Ayouba M. A, Maman M. I, Ikhiri K. Ethnobotanic investigation and phytochimic screening of some tinctorial plants of Niger for a valorization in solar energy. Int J Biol Chem Sci. 2018; 12(2):867. doi :10.4314/ijbcs.v12i2.20. In french
8. Elzagheid M. I., Laboratory Activities to Introduce Carbohydrates Qualitative Analysis to College Students. World J Chem Educ. 2018; 6(2):82-86. doi:10.12691/wjce-6-2-1
9. Olufunmiso O., Babalola A., Afolayan A., Antibacterial and phytochemical screening of crude ethanolic extracts of Waltheria indica Linn. Afr J Microbiol Res. 2011; 5. doi:10.5897/AJMR11.627
10. Okou O. C., Yapo S., Kouassi K. C., Guy L. B., Sylvia M., Allico J., D., Evaluation of the antibacterienne activity of the fruit extracts of Solanum torvum Swartz (Solanaceae) on in vitro growth of seven (07) stocks of enterobacteries of various profiles (resistant or sensitive). Int J Biol Chem Sci. 2019; 13(3):1510. doi :10.4314/ijbcs.v13i3.24. In french
11. Yao K., Otis T. B. I, Serge A., Djeneb C., Noël Z. G., Phytochemical Screening and Evaluation of the Cytotoxicity of Fruits of Solanum torvum Swartz (Solanaceae) on HFF Cells (Human Foreskin Fibroblasts). Asian J Res Bot. 2018:1-7.
12. Yousaf Z., Wang Y., Baydoun E., Phytochemistry and Pharmacological Studies on Solanum torvum Swartz. J Appl Pharm Sci.2013; 3(04):152-160. doi:10.7324/JAPS.2013.3428
13. Chah K. F., Muko K. N., Oboegbulem SI. Antimicrobial activity of methanolic extract of Solanum torvum fruit. Fitoterapia. 2000;71(2):187-189. doi:10.1016/S0367-326X (99)00139-2
14. Nawrot-Modranka J., Nawrot E., Synthesis, spectroscopy and alkylating properties of Pd (II) complexes of phosphorohydrazones of coumarin and chromone with potential antibacterial activity. Acta Pol Pharm-Drug Res. 2007; 64(5):429-434.
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