Evaluation of Antibiotic Prescription and Utilization amongst Hospitalized Children in a Tertiary Facility in Sokoto, North-Western Nigeria

ANTIBIOTIC USE IN ADMITTEC CHILDREN

  • Khadijat Omeneke Isezuo Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
  • UM Sani Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
  • BI Garba Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
  • UM Waziri Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
  • OB Okwuolise Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
  • A Adamu Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
  • FB Jiya Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
  • M Amodu-Sanni Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Abstract

Background: Antibiotics are the most widely utilized therapeutic agents. Inappropriate use causes increase cost and antibiotic resistance. The World Health Organization recommends assessment of antibiotics use to guide prescribing practices.


Objective: To describe the pattern of antibiotic usage among paediatric inpatients aged > 1 month to 15 years in a tertiary hospital in Sokoto, Nigeria.


Methods: Febrile children were recruited prospectively by systematic random sampling from January to October 2018. Socio-demographics, diagnosis, antibiotics administered were obtained from case notes. The WHO indicators of use of antibiotics were employed for evaluation. Data was analysed with SPSS version 23.


Results: Out of 352 children, 318 (90.3%) received antibiotics; commonest being Ceftriaxone in 155/318 (48.7%), Cefuroxime in 74 (23.2%), and Metronidazole in 29 (9.1%). Average number of antibiotics per patient was 2.3±1.1 with treatment duration of 4.3±1.4days. Antibiotic consumption was 937.2 days of antibiotic therapy/1000 patient days (DOT/PD). Generic name was used in 92.3% while 100% of the drugs were on the essential medicine list. Frequent diagnoses were severe malaria 98/352 (27.8%), respiratory infections 39 (11.1%) and severe malnutrition in 38 (10.8%). Only 6 (1.7%) patients had microbiologic evidence of infection.


Conclusion: Utilization of antibiotics is higher than recommended. There is need for improved diagnostic facilities to avoid antibiotic overuse and its consequences.


Keywords: antibiotics, prescription, utilization, children, inpatients, DOT

Keywords: antibiotics, prescription, utilization, children, inpatients, DOT

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Author Biographies

Khadijat Omeneke Isezuo, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

UM Sani, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

BI Garba, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

UM Waziri, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

OB Okwuolise, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

A Adamu, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

FB Jiya, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

M Amodu-Sanni, Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria

References

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Isezuo K, Sani U, Garba B, Waziri U, Okwuolise O, Adamu A, Jiya F, Amodu-Sanni M. Evaluation of Antibiotic Prescription and Utilization amongst Hospitalized Children in a Tertiary Facility in Sokoto, North-Western Nigeria. JDDT [Internet]. 15Jul.2020 [cited 29Sep.2020];10(4):31-6. Available from: http://www.jddtonline.info/index.php/jddt/article/view/4158