A Study on Drug Utilization of Antibiotics in Respiratory Tract Infections among Geriartrics

  • Sripuram Charave Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050
  • Reshmi Suresh Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050
  • , Shihab Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050
  • Mohammed Fayiz Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050
  • Apoorva Dev Assistant Professor, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Abstract

Back ground: Respiratory Tract Infections (RTIs) often pose a major threat for geriatric patients (>60 years) who are at higher risk of developing complications. The first line treatments for RTIs are antibiotics which help in reducing the infection. As there is increasing incidence of antimicrobial resistance it is necessary to conduct drug utilization of antibiotics which helps in better understanding about errors and risks involved in prescriptions.


Objectives: The objective of the study is to access the prescribing pattern, appropriate use of antibiotics and inappropriateness of antibiotics in viral infections.


Methodology: The present study is a prospective observational study. The study included 110 patients which included the evaluation of the patients medical records of antibiotics, sputum culture reports and physician records.


Results: Out of 110 geriartric RTI patients, female (59.09%) were more predominantly affected over males (40.90%). Among the RTIs diagnosed pneumonia (40%) was higher followed by LRTI (28.18%). The common signs and symptoms found were breathlessness (34.54%) with major comorbidity of diabetes milletus (47.31%). Piperacillin + tazobactam (40.90%) was the mostly prescribed antibiotic for both gram positive (Streptococci) and gram negative (E. coli) bacteria which was given through I.V. (90%). Total drug interactions and medication errors were 13.03% and 3.32% respectively.


Conclusion: The present study gives an overview of antibiotics use and complications involved in geriatric population diagnosed with RTIs. Appropriate antibiotic usage according to Hospital Antibiotic Policy was observed in the study site with lower number of medication errors and drug interactions.


Key words: Respiratory Tract Infections, drug utilization, antibiotics, geriatrics.

Keywords: Respiratory Tract Infections, drug utilization, antibiotics, geriatrics

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Author Biographies

Sripuram Charave, Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Reshmi Suresh, Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

, Shihab, Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Mohammed Fayiz, Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Pharm D Interns, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Apoorva Dev, Assistant Professor, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

Assistant Professor, Department of Pharmacy Practice, PES University, Bengaluru, Karnataka, India-560 050

References

1. Khan S, Priti S, Ankit S. Bacteria etiological agents causing lower respiratory tract infections and their resistance patterns. Iranian Biomedical Journal 2015; 19(4):240.
2. Akanbi MO, Ukoli CO, Erhabor GE, Akanbi FO, Gordon SB. The burden of respiratory disease in Nigeria. Afr J Respir Med 2009; 4:10-7.
3. Naik HG, Khanwelkar CC, Kolur A, Desai R, Gidamudi S. Drug utilization study on antibiotics use in the upper respiratory tract infection. International Journal of Recent Trends in Science and Technology 2014; 10(12):299-302.
4. Nieters A, Weber S, Elgizouli M. Screening score to identify people prone to respiratory tract infections in the community. Int J Respir Med 2017; 2(1):6-13.
5. Shamim, M., M. D. Ali, M. S. Alam, M. S. Ali, S. Ahmad, and M. S. Ansari. “Drug utilization based ADRs detection of antibiotics prescribed for lrti in tertiary care teaching hospital, New Delhi”. International Journal of Pharmacy and Pharmaceutical Sciences 2018; 10(4):7-14.
6. Tchatchouang S, Bigna JJ, Nzouankeu A, Fonkoua MC, Nansseu JR, Ndangang MS, Kenmoe S, Penlap VB, Njouom R. Prevalence of respiratory bacterial infections in people with lower respiratory tract infections in Africa: the BARIAFRICA systematic review and meta-analysis protocol. BMJ open. 2018; 8(9):e023592.
7. Andersen P. Pathogenesis of lower respiratory tract infections due to Chlamydia, Mycoplasma, Legionella and viruses. Thorax 1998; 53(4):302-7.
8. Ahmed MM, ELMaraghy AA, Andrawas EW. Study of prescription patterns of antibiotics in treating lower respiratory tract infections at Sohag Chest Hospital. Egyptian Journal of Chest Diseases and Tuberculosis 2016; 65(1):143-55.
9. Harris AM, Hicks LA, Qaseem A. Appropriate antibiotic use for acute respiratory tract infection in adults. Annals of Internal Medicine 2016; 165(9):674.
10. Etebu E, Arikekpar I. Antibiotics: Classification and mechanisms of action with emphasis on molecular perspectives. Int J Appl Microbiol Biotechnol Res 2016; 4:90-101.
11. Battula P, Reddy TM, Prasad TD, Diviti R. A Prospective Study on inappropriate Drug utilization in Geriatric Patients at A Tertiary Care Teaching Hospital. Indian Journal of Pharmacy Practice 2016; 9(3):179.
12. J.Mark Ruscin. Drug Related Problems in Elderly. https://www.msdmanuals.com/professional/geriatrics/drug-therapy-in-older-adults/drug-related-problems-in-older-adults
13. Parthasarathy G, Nyfort-hansen K, Milap N. Clinic Pharmacy Book: Essential Concepts and Skills. Pp. 362-72.
14. Gogineni Vinutna, Mallela Babji, Reshma Namburi, Raj Kumari. Drug utilization study in patients with acute respiratory tract infections at a tertiary care hospital in Bhimavaram, India. International Journal of Advance Research, Ideas and Innovations in Technology 2018: 3(9):
15. Hak E, Rovers MM, Kuyvenhoven MM, Schellevis FG, Verheij TJ. Incidence of GP-diagnosed respiratory tract infections according to age, gender and high-risk co-morbidity: the Second Dutch National Survey of General Practice. Family practice. 2006; 23(3):291-4.
16. Cacciatore F, Gaudiosi C, Mazzella F, Scognamiglio A, Mattucci I, Carone M, Ferrara N, Abete P. Pneumonia and hospitalizations in the elderly. GC [Internet]. 17May2017 [cited 14Apr.2019]; 3(1). Available from: https://www.pagepressjournals.org/index.php/gc/article/view/6377
17. Shiley KT, Lautenbach E, Lee I. The use of antimicrobial agents after diagnosis of viral respiratory tract infections in hospitalized adults: antibiotics or anxiolytics?. Infection Control & Hospital Epidemiology 2010; 31(11):1177-83.
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1.
Charave S, Suresh R, Shihab , Fayiz M, Dev A. A Study on Drug Utilization of Antibiotics in Respiratory Tract Infections among Geriartrics. JDDT [Internet]. 15Jun.2020 [cited 29Mar.2024];10(3-s):61-7. Available from: https://www.jddtonline.info/index.php/jddt/article/view/4084