Assessment of Healing Potential of Formulated Herbal Cream on Burn Wound

  • Yogesh Shivhare Sarvepalli Radhakrishnan University, Bhopal (M.P.) India
  • Alok Pal Jain Sarvepalli Radhakrishnan University, Bhopal (M.P.) India


The current protocol of the study was planned to assess the healing potential of formulated herbal cream containing different medicinal plant extracts. Formulated herbal cream was containing the methanolic extract of Chenopodium album, Coccinia indica, Momordica dioica, Precitrullus fistulosus and Trichosanthes dioica with cream base. Formulated herbal cream was assessed pharmacologically for healing potential in burn wound model. The formulation showed a significantly higher contraction rate, shortened epithelialization period, better tensile strength and increase in hydroxyproline content in the burn wound model. Thus, it is concluded that formulation has the potential wound healing activity which justifying its use as wound healer.

Keywords:  Formulation, Burn, Wound, Contraction

Keywords: Formulation, Burn, Wound, Contraction


Download data is not yet available.


1. Anonymous. 1994. Ethnobotany in the search for new drugs. Ciba Foundation Symposium 188, John Wiley and Sons, New York.
2. Fabricant DS, Farnsworth NR. The value of plants used in traditional medicine for drug discovery. Environ Health Perspective. 2001; 109:69-75.
3. Taylor Leslie ND. Plant Based Drugs and Medicines. Rain Tree Nutrition. 2000.
4. Bhatia Nitish, Singh Arunpreet, Sharma Rohit, Singh Amandeep, Soni Varinder, Singh Gurjeet, Bajaj Jaideep, Dhawan Ravi, Singh Balwinder. Evaluation of burn wound healing potential of aqueous extract of Morus alba based cream in rats. The Journal of Phytopharmacology. 2014; 3(6):378-383.
5. Manafi A, Kohanteb J, Mehrabani D, Japoni A, Amini M, Naghmachi M, Zaghi AH, Khalili N. Active immunization using exotoxin A confers protection against Pseudomonas aeruginosa infection in a mouse burn model. BMC Microbiology. 2009; 9:23.
6. Das Trailokya, Debnath Jiban, Nath Bipul, Dash Suvakanta. Formulation and evaluation of an herbal cream for wound healing activity. International Journal of Pharmacy and Pharmaceutical Sciences. 2014; 6 (2):693-697.
7. Nair Sujith S, Mathew Molly, Sreena K. Formulation and Evaluation of Herbal Cream containing Curcuma longa. International Journal of Pharmaceutical and Chemical Sciences. 2012; 1 (4):1362-1368.
8. Kubo I, Muroi H, Kubo A. Naturally Occurring Anti-acne Agents. Journal of Natural Products. 1994; 57(1):9-17.
9. Vijayalakshmi A, Tripura A, Ravichandiran V. Development and Evaluation of Anti- Acne Products from Terminalia arjuna Bark. International Journal of Chem Tech Research. 2011; 3(1):320-327.
10. Shanmuga Priya K, Gnanamani A, Radhakrishnan N, Babu Mary. Healing potential of Datura alba on burn wounds in albino rats. Journal of Ethnopharmacology. 2002; 83:193-199.
147 Views | 161 Downloads
How to Cite
Shivhare Y, Jain AP. Assessment of Healing Potential of Formulated Herbal Cream on Burn Wound. JDDT [Internet]. 5Feb.2020 [cited 26Jan.2022];9(4-s):1191-4. Available from: