Phytochemical Screening and Anti-Diabetic and Anti-Hyperlipidemic Activity of Ethanolic Fruits Extract of Scindapsus Officinalis (Roxb)

  • Pawan Tiwari Department of Pharmaceutical Chemistry, Bhupal Nobel University, Udaipur, Rajasthan, India.
  • Anju Goyal Department of Pharmaceutical Chemistry, Bhupal Nobel University, Udaipur, Rajasthan, India.

Abstract

The present research work emphasized on evaluates the Phytochemical & Pharmacological activities of the fruits of Scindapsus Officinalis (Roxb) (Araceae). The fruits of the plant were shade dried, reduced to coarse powder with the help of grinder was subjected to successive soxhlet extraction with Petroleum Ether and 90% v/v Ethanol (Emparta). The various extracts were then subjected to preliminary phytochemical screening which revealed the presence of flavonoids, saponins, tannins, phenols, carbohydrate, lipids, alkaloids & steroids. Selection of active extract for in vivo studies was based on preliminary phytochemical tests and in vitro glucose diffusion inhibition potential and accordingly, ethanolic extracts were chosen for further studies. The pharmacological screening included evaluation of the antidiabetic and hypolipidemic activity of ethanolic extracts (200mg/kg and 400mg/kg b.w) on Streptozotocin-induced diabetic rats. The ethanolic extract was found to be more effective and brought about significant antidiabetic & hypolipidemic potential. This was due to the presence of one or more phytoconstituents present in ethanol extract.


Keywords: Scindapsus Officinalis (Roxb); Antidiabetic; Anti-hyperlipidemic; Streptozotocin.

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Tiwari P, Goyal A. Phytochemical Screening and Anti-Diabetic and Anti-Hyperlipidemic Activity of Ethanolic Fruits Extract of Scindapsus Officinalis (Roxb). JDDT [Internet]. 12Dec.2019 [cited 29Nov.2021];9(4-s):1072-86. Available from: http://www.jddtonline.info/index.php/jddt/article/view/3781