Nanotechnology: Emerging Platform for Drug Based Delivery System in Cancer
In present scenario cancer has become one of the most difficult global healthcare problems, despite of having library of anti-cancer drugs the problem remains the same due to no specificity, burst release, damaging of normal cells and numerous side effects. Nanotechnology the emerging field gained attention as it offers site specific treatment in various tumors with lesser side effect. Nano carriers, a transport module provide platform to circumvent the problems related with the delivery of anticancer drug in drug delivery systems. Nano carriers help to improve the bioavailability and therapeutic efficiency of antitumor drugs, while providing preferential accumulation at the target site. Various nanocarriers are clinically approved for the delivery of antitumor drugs for their intended actions at the targeted sites. This review illustrates about the various nanocarriers, their importance in the delivery of anticancer drugs, targeting mechanisms of nanoparticles, various method of preparations of nanoparticles and influence of nanotechnology on herbal drug.
Keywords: Nanocarrier, bioavailability, multi drug resistance,
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