Breast Cancer- In 21st Century Current Status and Future Perspective

Abstract

The most frequent cancer type in females in the world is breast cancer; with a lifetime risk of the order of 1/10.Breast cancer is the most common invasive cancer in females. It usually presents with a lump in the breast with or without other manifestations. The tumor is malignant (cancer) if the cells can grow into (invade) surrounding tissues or spread (metastasize) to distant areas of the body. Breast cancers can start from different parts of the breast. Our understanding of the molecular events relating to breast cancer biology and pathogenesis has greatly increased over the last decade. Diagnosis of breast cancer depends on physical examination, mammographic findings and biopsy results. Treatment of breast cancer depends on the stage of the disease. Lines of treatment include mainly surgical removal of the tumor followed by radiotherapy or chemotherapy. Second lines including immunotherapy and other therapy and alternative medicine may represent a hope for breast cancer patients.

Keyworld- breast cancer, lump, molecular events, biology and pathogenesis, radiotherapy.